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FAP Antikörper (N-Term)

Name: FAP Antikörper (N-Term)
SKU: ABIN1881337
Price: 445.5 EUR
Availability: InStock

FAP Reaktivität: Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB40867 unconjugated

Anti-Mouse Fap Antibody (N-term) at 1:2000 dilution + mouse kidney lysate Lysates/proteins at 20 μg per lane. (FAP Antikörper (N-Term))

Immunohistochemical analysis of (ABIN1881337 and ABIN2838726) on paraffin-embedded Mouse kidney tissue. (FAP Antikörper (N-Term))

IHC (p)

All lanes : Anti-Mouse Fap Antibody (N-term) at 1:500 dilution Lane 1: Mouse kidney lysate Lane 2: Mouse ovary lysate Lysates/proteins at 20 μg per lane. (FAP Antikörper (N-Term))

3 Abbildungen

(3 Referenzen)

Produktnummer ABIN1881337

Datenblatt (PDF)

Target Alle FAP Antikörper anzeigen

FAP (Fibroblast Activation Protein, alpha (FAP))
Bindungsspezifität
16

6

5

4

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 15-41, N-Term
Reaktivität
63

33

22

14

6

5

2

1

1

1

1

1

1

1
Maus
Wirt
59

11
Kaninchen
Passende Sekundärantikörper
Klonalität
57

13
Polyklonal
Konjugat
44

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser FAP Antikörper ist unkonjugiert
Applikation
60

24

19

13

13

11

10

5

4

4

4

3

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This Mouse Fap antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-41 amino acids from the N-terminal region of mouse Fap.

Klon

RB40867

Isotyp

Ig Fraction

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anti-Fibroblast Activation Protein, alpha (FAP) (AA 26-280) antibody
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Applikationshinweise

WB: 1:2000. WB: 1:500. IHC-P: 1:100

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Haltbarkeit

6 months
Wen, Wang, Ma, Li, Zhou, Mu, Leng, Shi, Li, Wei: "Immunotherapy targeting fibroblast activation protein inhibits tumor growth and increases survival in a murine colon cancer model." in: Cancer science, Vol. 101, Issue 11, pp. 2325-32, (2010) (PubMed).

Santos, Jung, Aziz, Kissil, Puré: "Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice." in: The Journal of clinical investigation, Vol. 119, Issue 12, pp. 3613-25, (2009) (PubMed).

Kennedy, Dong, Chen, Chen: "Elevation of seprase expression and promotion of an invasive phenotype by collagenous matrices in ovarian tumor cells." in: International journal of cancer. Journal international du cancer, Vol. 124, Issue 1, pp. 27-35, (2008) (PubMed).
Target

FAP (Fibroblast Activation Protein, alpha (FAP))

Andere Bezeichnung

Fap (FAP Produkte)

Synonyme

fap-A antikoerper, gene 13 antikoerper, FAP antikoerper, fapa antikoerper, dppiv antikoerper, seprase antikoerper, DPPIV antikoerper, FAPA antikoerper, fibroblast activation protein antikoerper, fibroblast activation protein alpha L homeolog antikoerper, fibroblast activation protein alpha antikoerper, fibroblast activation protein, alpha antikoerper, prolyl endopeptidase FAP antikoerper, Fap antikoerper, fap.L antikoerper, FAP antikoerper, fap antikoerper, LOC100547273 antikoerper

Hintergrund

In association with DPP4 is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM (By similarity). May have a role in tissue remodeling during development and wound healing, and contribute to invasiveness in malignant cancers.

Molekulargewicht

87945

NCBI Accession

NP_032012

UniProt

P97321

Pathways

Tube Formation