UIMC1 Antikörper (ubiquitinated)

Produktnummer ABIN7603469

Dieses Anti-UIMC1-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von UIMC1 in WB, IHC, IF und ICC. Geeignet für Human.

Kurzübersicht für UIMC1 Antikörper (ubiquitinated) (ABIN7603469)

Target: UIMC1 (Ubiquitin Interaction Motif Containing 1 (UIMC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser UIMC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: ADCH-21

Produktdetails anti-UIMC1 Antikörper

Bindungsspezifität: ubiquitinated

Verwendungszweck: Anti-RAP80 Monoclonal Antibody

Produktmerkmale: Anti-RAP80 Monoclonal Antibody (ABIN7603469). Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human.

Aufreinigung: Affinity-chromatography

Immunogen: A synthesized peptide derived from human RAP80 Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Plays a central role in the BRCA1-A complex by specifically binding 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs) .

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:5000
IHC 1:50-1:200
ICC/IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Konzentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Details zu UIMC1

Target: UIMC1 (Ubiquitin Interaction Motif Containing 1 (UIMC1))

Andere Bezeichnung: UIMC1

Hintergrund:

Synonyms: Tumor necrosis factor receptor superfamily member 12A,Fibroblast growth factor-inducible immediate-early response protein 14,FGF-inducible 14,Tweak-receptor,TweakR,CD266,TNFRSF12A,FN14,

Tissue Specificity: Highly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas.

Molekulargewicht: 70,90 kDa

Pathways: DNA Reparatur, Nuclear Hormone Receptor Binding, Positive Regulation of Response to DNA Damage Stimulus