S100A14 Antikörper (C-Term)

Produktnummer ABIN7602920

Produktdetails anti-S100A14 Antikörper

Target: S100A14 (S100 Calcium Binding Protein A14 (S100A14))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser S100A14 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Verwendungszweck: Anti-S100A14 Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-A14 Antibody Picoband® (ABIN7602920). Tested in IHC applications. This antibody reacts with Human.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human S100A14, which shares 93.8% amino acid (aa) sequence identity with mouse S100A14.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
1. Adam, P. J., Boyd, R., Tyson, K. L., Fletcher, G. C., Stamps, A., Hudson, L., Poyser, H. R., Redpath, N., Griffiths, M., Steers, G., Harris, A. L., Patel, S., Berry, J., Loader, J. A., Townsend, R. R., Daviet, L., Legrain, P., Parekh, R., Terrett, J. A. Comprehensive proteomic analysis of breast cancer cell membranes reveals unique proteins with potential roles in clinical cancer. J. Biol. Chem. 278: 6482-6489, 2003. 2. Chen, H., Yu, D., Luo, A., Tan, W., Zhang, C., Zhao, D., Yang, M., Liu, J., Lin, D., Liu, Z. Functional role of S100A14 genetic variants and their association with esophageal squamous cell carcinoma. Cancer Res. 69: 3451-3457, 2009. 3. Pietas, A., Schluns, K., Marenholz, I., Schafer, B. W., Heizmann, C. W., Petersen, I. Molecular cloning and characterization of the human S100A14 gene encoding a novel member of the S100 family. Genomics 79: 513-522, 2002.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu S100A14

Target: S100A14 (S100 Calcium Binding Protein A14 (S100A14))

Andere Bezeichnung: S100A14 (S100A14 Produkte)

Hintergrund:

Synonyms: ELAV-like protein 2, ELAV-like neuronal protein 1, Hu-antigen B, HuB, Nervous system-specific RNA-binding protein Hel-N1, ELAVL2, HUB

Tissue Specificity: Brain, neural-specific.

Background: S100 calcium binding protein A14 (S100A14) is a protein that in humans is encoded by the S100A14 gene. This gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function.

Molekulargewicht: 18 kDa

Gen-ID: 57402

Pathways: Activation of Innate immune Response, S100 Proteine