CD15 Antikörper (C-Term)

Produktnummer ABIN7602822

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CD15 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD15 Antikörper (C-Term) (ABIN7602822)

Target: CD15 (FUT4) (Fucosyltransferase 4 (Alpha (1,3) Fucosyltransferase, Myeloid-Specific) (FUT4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CD15 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Anti-FUT4 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-FUT4 Antibody (ABIN7602822). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human FUT4, which shares 72.7% and 71.4% amino acid (aa) sequence identity with mouse and rat FUT4, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
1. Cailleau-Thomas, A., Coullin, P., Candelier, J.-J., Balanzino, L., Mennesson, B., Oriol, R., Mollicone, R. FUT4 and FUT9 genes are expressed early in human embryogenesis. Glycobiology 10: 789-802, 2000. 2. Couillin, P., Mollicone, R., Grisard, M. C., Gibaud, A., Ravise, N., Feingold, J., Oriol, R. Chromosome 11q localization of one of the three expected genes for the human alpha-3-fucosyltransferases, by somatic hybridization. Cytogenet. Cell Genet. 56: 108-111, 1991. 3. Gersten, K. M., Natsuka, S., Trinchera, M., Petryniak, B., Kelly, R. J., Hiraiwa, N., Jenkins, N. A., Gilbert, D. J., Copeland, N. G., Lowe, J. B. Molecular cloning, expression, chromosomal assignment, and tissue-specific expression of a murine alpha-(1,3)-fucosyltransferase locus corresponding to the human ELAM-1 ligand fucosyl transferase. J. Biol. Chem. 270: 25047-25056, 1995.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu CD15

Target: CD15 (FUT4) (Fucosyltransferase 4 (Alpha (1,3) Fucosyltransferase, Myeloid-Specific) (FUT4))

Andere Bezeichnung: FUT4

Hintergrund:

Synonyms: Ras-related protein Rab-11B, GTP-binding protein YPT3, RAB11B, YPT3

Tissue Specificity: Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.

Background: Fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific), also known as FUT4, is an enzyme which in humans is encoded by the FUT4 gene. The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15).

Molekulargewicht: 70 kDa

Gen-ID: 2526

UniProt: P22083