LIMA1 Antikörper (AA 9-744)
Kurzübersicht für LIMA1 Antikörper (AA 9-744) (ABIN7602639)
Target
Alle LIMA1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
 - AA 9-744
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Verwendungszweck
 - Anti-EPLIN/LIMA1 Antibody Picoband®
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Kreuzreaktivität (Details)
 - No cross-reactivity with other proteins.
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Produktmerkmale
 - Anti-EPLIN/LIMA1 Antibody Picoband® (ABIN7602639). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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Aufreinigung
 - Immunogen affinity purified.
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Immunogen
 - E.coli-derived human EPLIN/LIMA1 recombinant protein (Position: R9-E744).
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Isotyp
 - IgG
 
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Applikationshinweise
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                        Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chen, S., Maul, R. S., Kim, H. R., Chang, D. D. Characterization of the human EPLIN (Epithelial Protein Lost in Neoplasm) gene reveals distinct promoters for the two EPLIN isoforms. Gene 248: 69-76, 2000. 2. Maul, R. S., Chang, D. D. EPLIN, epithelial protein lost in neoplasm. Oncogene 18: 7838-7841, 1999. 3. Maul, R. S., Song, Y., Amann, K. J., Gerbin, S. C., Pollard, T. D., Chang, D. D. EPLIN regulates actin dynamics by cross-linking and stabilizing filaments. J. Cell Biol. 160: 399-407, 2003. - 
                                            
Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Format
 - Lyophilized
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Rekonstitution
 - Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Konzentration
 - 500 μg/mL
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Buffer
 - Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Lagerung
 - 4 °C,-20 °C
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Informationen zur Lagerung
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                        At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. 
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. 
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- LIMA1 (LIM Domain and Actin Binding 1 (LIMA1))
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Andere Bezeichnung
 - LIMA1
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Hintergrund
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Synonyms: Zinc finger protein Helios, Ikaros family zinc finger protein 2, IKZF2, HELIOS, ZNFN1A2
Tissue Specificity: Ubiquitous. High expression in liver, spleen, pancreas and kidney.
Background: LIM domain and actin-binding protein 1 is a protein that in humans is encoded by the LIMA1 gene. This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and expression of some of the variants maybe independently regulated.
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Molekulargewicht
 - 85 kDa, 100 kDa
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Gen-ID
 - 51474
 
Target
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