DBN1 Antikörper (AA 9-649)

Produktnummer ABIN7602637

Der Maus-Monoklonal Anti-DBN1-Antikörper wurde für WB, IHC und FACS validiert. Er ist geeignet zum Nachweis von DBN1 in Proben aus Human, Maus, Ratte und Affe. }

Kurzübersicht für DBN1 Antikörper (AA 9-649) (ABIN7602637)

Target: DBN1 (Drebrin 1 (DBN1))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DBN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Klon: 4F6E7

Produktdetails anti-DBN1 Antikörper

Bindungsspezifität: AA 9-649

Verwendungszweck: Anti-Drebrin/DBN1 Antibody (monoclonal, 4F6E7)

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Drebrin/DBN1 Antibody (monoclonal, 4F6E7) (ABIN7602637). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat, Monkey. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Drebrin/DBN1 recombinant protein (Position: H9-D649).

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat, Monkey
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu DBN1

Target: DBN1 (Drebrin 1 (DBN1))

Andere Bezeichnung: DBN1

Hintergrund:

Synonyms: Cytochrome c oxidase subunit 4 isoform 1, mitochondrial, Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit IV isoform 1, COX IV-1, COX4I1, COX4

Tissue Specificity: Highly expressed in liver. Expressed in testis and weakly in colon.

Background: Drebrin is a protein that in humans is encoded by the DBN1 gene. The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.

Molekulargewicht: 120 kDa

Gen-ID: 1627

UniProt: Q16643

Pathways: Maintenance of Protein Location