DBN1 Antikörper (AA 1-326)
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- Target Alle DBN1 Antikörper anzeigen
- DBN1 (Drebrin 1 (DBN1))
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Bindungsspezifität
- AA 1-326
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser DBN1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Cytometry by Time of Flight (CyTOF)
- Spezifität
- The mouse monoclonal antibody DBN-N-03 recognizes drebrin, an approximately 100-125 kDa intracellular regulator of actin cytoskeleton.
- Kreuzreaktivität (Details)
- Human
- Aufreinigung
- Purified by protein-A affinity chromatography.
- Reinheit
- > 95 % (by SDS-PAGE)
- Immunogen
- Bacterially expressed N-terminal fragment of recombinant human drebrin (aa 1-326)
- Klon
- DBN-N-03
- Isotyp
- IgG2b
- Top Product
- Discover our top product DBN1 Primärantikörper
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anti-Drebrin 1 (DBN1) (AA 150-281) antibody
DBN1 Reaktivität: Human IHC, StM Wirt: Maus Monoclonal DBN1-2879 unconjugated
anti-Drebrin 1 (DBN1) (AA 1-326) antibody (PE)DBN1 Reaktivität: Human FACS Wirt: Maus Monoclonal DBN-N-03 PE
anti-Drebrin 1 (DBN1) (Internal Region) antibodyDBN1 Reaktivität: Human, Maus, Ratte WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Drebrin 1 (DBN1) (AA 1-649) antibodyDBN1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2E11 unconjugated
anti-Drebrin 1 (DBN1) (AA 350-649) antibodyDBN1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Drebrin 1 (DBN1) (AA 401-596) antibodyDBN1 Reaktivität: Human WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Drebrin 1 (DBN1) (AA 3-134) antibodyDBN1 Reaktivität: Human WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Drebrin 1 (DBN1) (AA 151-250) antibodyDBN1 Reaktivität: Human, Maus, Ratte WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Drebrin 1 (DBN1) (AA 194-228) antibodyDBN1 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB56246 unconjugated
anti-Drebrin 1 (DBN1) antibodyDBN1 Reaktivität: Human IF Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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Western blotting: Positive control: REH, Nalm-6, HEK293 cells.
Flow cytometry: Recommended dilution: 1-4 μg/mL. Intracellular staining. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- Target
- DBN1 (Drebrin 1 (DBN1))
- Andere Bezeichnung
- Drebrin (DBN1 Produkte)
- Synonyme
- D0S117E antikoerper, DBN1 antikoerper, LOC733967 antikoerper, drebrin 1 antikoerper, drebrin 1 S homeolog antikoerper, DBN1 antikoerper, Dbn1 antikoerper, dbn1.S antikoerper, dbn1 antikoerper
- Hintergrund
- Drebrin 1,Drebrin is an actin-binding protein, which is expressed mainly in neurons and plays important role in their morphogenesis. The highest level of its expression is in developing brain. Both in neurons and non-neuronal cells drebrin acts as a key regulator of actin cytoskeleton remodelling, affecting especially intercellular junctions, such as dendritic spines of neurons or the immune synapses of T cells. Decrease of drebrin amount in the brain seems to be associated with Alzheimer's disease and Down syndrome, and in case of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) lower drebrin expression correlates with higher risk of relapse.,DBN, D0S117E
- Gen-ID
- 1627
- UniProt
- Q16643
- Pathways
- Maintenance of Protein Location
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