Sorting Nexin 1 Antikörper (AA 83-505)

Produktnummer ABIN7602548

Dieses Anti-Sorting Nexin 1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Sorting Nexin 1 in WB, ELISA, IHC, IF, ICC und FACS. Geeignet für Human.

Kurzübersicht für Sorting Nexin 1 Antikörper (AA 83-505) (ABIN7602548)

Target: Sorting Nexin 1 (SNX1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Sorting Nexin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Produktdetails anti-Sorting Nexin 1 Antikörper

Bindungsspezifität: AA 83-505

Verwendungszweck: Anti-SNX1 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-SNX1 Antibody Picoband® (ABIN7602548). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SNX1 recombinant protein (Position: Q83-Q505).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chen, D., Xiao, H., Zhang, K., Wang, B., Gao, Z., Jian, Y., Qi, X., Sun, J., Miao, L., Yang, C. Retromer is required for apoptotic cell clearance by phagocytic receptor recycling. Science 327: 1261-1264, 2010. 2. Haft, C. R., de la Luz Sierra, M., Barr, V. A., Haft, D. H., Taylor, S. I. Identification of a family of sorting nexin molecules and characterization of their association with receptors. Molec. Cell. Biol. 18: 7278-7287, 1998. 3. Kurten, R. C., Cadena, D. L., Gill, G. N. Enhanced degradation of EGF receptors by a sorting nexin, SNX1. Science 272: 1008-1010, 1996.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu Sorting Nexin 1

Target: Sorting Nexin 1 (SNX1)

Andere Bezeichnung: SNX1

Hintergrund:

Synonyms: Neuronal PAS domain-containing protein 2,Neuronal PAS2,Basic-helix-loop-helix-PAS protein MOP4,Class E basic helix-loop-helix protein 9,bHLHe9,Member of PAS protein 4,PAS domain-containing protein 4,NPAS2,BHLHE9, MOP4, PASD4,

Background: Sorting nexin-1 is a protein that in humans is encoded by the SNX1 gene. This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms.

Molekulargewicht: 70-75 kDa

Gen-ID: 6642

UniProt: Q13596