OPLAH Antikörper (AA 788-1072)

Produktnummer ABIN7602454

Produktdetails anti-OPLAH Antikörper

Target: OPLAH (5-Oxoprolinase (ATP-Hydrolysing) (OPLAH))

Bindungsspezifität: AA 788-1072

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OPLAH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)

Verwendungszweck: Anti-OPLAH Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-OPLAH Antibody Picoband® (ABIN7602454). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human OPLAH recombinant protein (Position: H788-E1072).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Almaghlouth, I. A., Mohamed, J. Y., Al-Amoudi, M., Al-Ahaidib, L., Al-Odaib, A., Alkuraya, F. S. 5-Oxoprolinase deficiency: report of the first human OPLAH mutation. Clin. Genet. 82: 193-196, 2012. 2. Calpena, E., Casado, M., Martinez-Rubio, D., Nascimento, A., Colomer, J., Gargallo, E., Garcia-Cazorla, A., Palau, F., Artuch, R., Espinos, C. 5-Oxoprolinuria in heterozygous patients for 5-oxoprolinase (OPLAH) missense changes. JIMD Rep. 7: 123-128, 2013. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 9/22/2011.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu OPLAH

Target: OPLAH (5-Oxoprolinase (ATP-Hydrolysing) (OPLAH))

Andere Bezeichnung: OPLAH (OPLAH Produkte)

Hintergrund:

Synonyms: Protein eva-1 homolog A, Protein FAM176A, Transmembrane protein 166, EVA1A, FAM176A, TMEM166, SP24

Tissue Specificity: Expressed in lung, kidney, liver, pancreas, placenta, but not in heart and skeletal muscle.

Background: The protein encoded by this gene acts as a homodimer, using ATP hydrolysis to catalyze the conversion of 5-oxo-L-proline to L-glutamate. Defects in this gene are a cause of 5-oxoprolinase deficiency (OPLAHD).

Molekulargewicht: 140 kDa

Gen-ID: 26873

UniProt: O14841