TIMELESS Antikörper (AA 72-1050)

Produktnummer ABIN7602369

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TIMELESS in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TIMELESS Antikörper (AA 72-1050) (ABIN7602369)

Target: TIMELESS (Timeless Homolog (TIMELESS))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIMELESS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TIMELESS Antikörper

Bindungsspezifität: AA 72-1050

Verwendungszweck: Anti-TIMELESS Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-TIMELESS Antibody Picoband® (ABIN7602369). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human TIMELESS recombinant protein (Position: Q72-E1050).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Barnes, J. W., Tischkau, S. A., Barnes, J. A., Mitchell, J. W., Burgoon, P. W., Hickok, J. R., Gillette, M. U. Requirement of mammalian timeless for circadian rhythmicity. Science 302: 439-442, 2003. Note: Erratum: Science 302: 1153 only, 2003. 2. Busza, A., Emery-Le, M., Rosbash, M., Emery, P. Roles of the two Drosophila CRYPTOCHROME structural domains in circadian photoreception. Science 304: 1503-1506, 2004. 3. Chan, R. C., Chan, A., Jeon, M., Wu, T. F., Pasqualone, D., Rougvie, A. E., Meyer, B. J. Chromosome cohesion is regulated by a clock gene paralogue TIM-1. Nature 423: 1002-1009, 2003.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu TIMELESS

Target: TIMELESS (Timeless Homolog (TIMELESS))

Andere Bezeichnung: TIMELESS

Hintergrund:

Synonyms: Protein argonaute-1,Argonaute1,hAgo1,Argonaute RISC catalytic component 1,Eukaryotic translation initiation factor 2C 1,eIF-2C 1,eIF2C 1,Putative RNA-binding protein Q99,AGO1,EIF2C1,

Tissue Specificity: Detected in blood plasma (at protein level).

Background: The protein encoded by this gene is highly conserved and is involved in cell survival after damage or stress, increase in DNA polymerase epsilon activity, maintenance of telomere length, and epithelial cell morphogenesis. The encoded protein also plays a role in the circadian rhythm autoregulatory loop, interacting with the PERIOD genes (PER1, PER2, and PER3) and others to downregulate activation of PER1 by CLOCK/ARNTL. Changes in this gene or its expression may promote prostate cancer, lung cancer, breast cancer, and mental disorders.

Molekulargewicht: 160 kDa

Gen-ID: 8914

Pathways: Protein targeting to Nucleus, Photoperiodism