Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

CRABP1 Antikörper (AA 60-118)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CRABP1 in WB, ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7602147

Kurzübersicht für CRABP1 Antikörper (AA 60-118) (ABIN7602147)

Target

Alle CRABP1 Antikörper anzeigen
CRABP1 (Cellular Retinoic Acid Binding Protein 1 (CRABP1))

Reaktivität

  • 29
  • 13
  • 1
Human

Wirt

  • 26
  • 3
Kaninchen

Klonalität

  • 24
  • 5
Polyklonal

Konjugat

  • 17
  • 4
  • 3
  • 3
  • 1
  • 1
Dieser CRABP1 Antikörper ist unkonjugiert

Applikation

  • 25
  • 21
  • 20
  • 5
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • Bindungsspezifität

    • 9
    • 8
    • 2
    • 2
    • 1
    AA 60-118

    Verwendungszweck

    Anti-CRABP1 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-CRABP1 Antibody Picoband® (ABIN7602147). Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human CRABP1 recombinant protein (Position: R60-E118).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Flagiello, D., Apiou, F., Gibaud, A., Poupon, M. F., Dutirllaux, B., Malfoy, B. Assignment of the genes for cellular retinoic acid binding protein 1 (CRABP1) and 2 (CRABP2) to human chromosome band 15q24 and 1q21.3, respectively, by in situ hybridization. Cytogenet. Cell Genet. 76: 17-18, 1997. 2. Geurts van Kessel, A., de Leeuw, H., Dekker, E. J., Rijks, L., Spurr, N., Ledbetter, D., Kootwijk, E., Vaessen, M. J. Localization of the cellular retinoic acid binding protein (CRABP) gene relative to the acute promyelocytic leukemia-associated breakpoint on human chromosome 15. Hum. Genet. 87: 201-204, 1991. 3. Guidez, F., Parks, S., Wong, H., Jovanovic, J. V., Mays, A., Gilkes, A. F., Mills, K. I., Guillemin, M.-C., Hobbs, R. M., Pandolfi, P. P., de The, H., Solomon, E., Grimwade, D. RAR-alpha-PLZF overcomes PLZF-mediated repression of CRABPI, contributing to retinoid resistance in t(11,17) acute promyelocytic leukemia. Proc. Nat. Acad. Sci. 104: 18694-18699, 2007.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    CRABP1 (Cellular Retinoic Acid Binding Protein 1 (CRABP1))

    Andere Bezeichnung

    CRABP1

    Hintergrund

    Synonyms: DAZ-associated protein 1, Deleted in azoospermia-associated protein 1, DAZAP1

    Tissue Specificity: Mainly expressed in testis. Expressed to a lower level in thymus. Weakly or not expressed in heart, liver, brain, placenta, lung, skeletal muscle, kidney and pancreas.

    Background: Cellular retinoic acid-binding protein 1 is a protein that in humans is encoded by the CRABP1 gene. This gene encodes a specific binding protein for a vitamin A family member and is thought to play an important role in retinoic acid-mediated differentiation and proliferation processes. It is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-ed differentiation in epithelial tissue.

    Molekulargewicht

    16 kDa

    Gen-ID

    1381

    UniProt

    P29762
Sie sind hier:
Chat with us!