PEX19 Antikörper (AA 51-269)

Produktnummer ABIN7601929

Der Kaninchen Polyklonal Anti-PEX19-Antikörper wurde für WB, ELISA und FACS validiert. Er ist geeignet, PEX19 in Proben von Human zu detektieren.

Kurzübersicht für PEX19 Antikörper (AA 51-269) (ABIN7601929)

Target: PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PEX19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-PEX19 Antikörper

Bindungsspezifität: AA 51-269

Verwendungszweck: Anti-PEX19 Antibody Picoband®

Produktmerkmale: Anti-PEX19 Antibody Picoband® (ABIN7601929). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PEX19 recombinant protein (Position: Q51-A269). Human PEX19 shares 91.8% and 94.5% amino acid (aa) sequence identity with mouse and rat PEX19, respectively.

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Braun, A., Kammerer, S., Weissenhorn, W., Weiss, E. H., Cleve, H. Sequence of a putative human housekeeping gene (HK33) localized on chromosome 1. Gene 146: 291-295, 1994. 2. Gotte, K., Girzalsky, W., Linkert, M., Baumgart, E., Kammerer, S., Kunau, W.-H., Erdmann, R. Pex19p, a farnesylated protein essential for peroxisome biogenesis. Molec. Cell. Biol. 18: 616-628, 1998. 3. James, G. L., Goldstein, J. L., Pathak, R. K., Anderson, R. G. W., Brown, M. S. PxF, a prenylated protein of peroxisomes J. Biol. Chem. 269: 14182-14190, 1994.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu PEX19

Target: PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))

Andere Bezeichnung: PEX19

Hintergrund: Peroxisomal biogenesis factor 19 is a protein that in humans is encoded by the PEX19 gene. This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 38 kDa

Gen-ID: 5824

UniProt: P40855