PEX19 Antikörper (AA 1-299)

Produktnummer ABIN6145463

Produktdetails anti-PEX19 Antikörper

Target: PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))

Bindungsspezifität: AA 1-299

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PEX19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: MAAAEEGCSV GAEADRELEE LLESALDDFD KAKPSPAPPS TTTAPDASGP QKRSPGDTAK DALFASQEKF FQELFDSELA SQATAEFEKA MKELAEEEPH LVEQFQKLSE AAGRVGSDMT SQQEFTSCLK ETLSGLAKNA TDLQNSSMSE EELTKAMEGL GMDEGDGEGN ILPIMQSIMQ NLLSKDVLYP SLKEITEKYP EWLQSHRESL PPEQFEKYQE QHSVMCKICE QFEAETPTDS ETTQKARFEM VLDLMQQLQD LGHPPKELAG EMPPGLNFDL DALNLSGPPG ASGEQCLIM

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-299 of human PEX19 (NP_002848.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-PEX19 Antikörper (ABIN6145463)

Zhou, Yu, Arshad, Wang, Lu, Gong, Gu, Li, Xu: "Coordination Among Lipid Droplets, Peroxisomes, and Mitochondria Regulates Energy Expenditure Through the CIDE-ATGL-PPARα Pathway in Adipocytes." in: Diabetes, Vol. 67, Issue 10, pp. 1935-1948, (2018) (PubMed).

Details zu PEX19

Target: PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))

Andere Bezeichnung: PEX19 (PEX19 Produkte)

Synonyme: BEST:GH03076 antikoerper, CG5325 antikoerper, DmelPex19 antikoerper, Dmel\\CG5325 antikoerper, D1S2223E antikoerper, HK33 antikoerper, PBD12A antikoerper, PMP1 antikoerper, PMPI antikoerper, PXF antikoerper, PXMP1 antikoerper, Pxf antikoerper, PxF antikoerper, Peroxin-19 antikoerper, Peroxin 19 antikoerper, Peroxisomal farnesylated protein antikoerper, peroxisomal biogenesis factor 19 antikoerper, Pex19 antikoerper, Bm1_19905 antikoerper, PEX19 antikoerper

Hintergrund: This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.,PEX19,D1S2223E,HK33,PBD12A,PMP1,PMPI,PXF,PXMP1,Signal Transduction,PEX19

Molekulargewicht: 29 kDa/32 kDa

Gen-ID: 5824

UniProt: P40855