SMC6 Antikörper (AA 499-1018)

Produktnummer ABIN7601864

Dieses Anti-SMC6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SMC6 in WB, ELISA, IHC, IF, ICC und FACS. Geeignet für Human und Ratte.

Kurzübersicht für SMC6 Antikörper (AA 499-1018) (ABIN7601864)

Target: SMC6 (SMC6 Structural Maintenance of Chromosomes 6-Like 1 (SMC6))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMC6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Produktdetails anti-SMC6 Antikörper

Bindungsspezifität: AA 499-1018

Verwendungszweck: Anti-SMC6 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-SMC6 Antibody Picoband® (ABIN7601864). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SMC6 recombinant protein (Position: H499-D1018).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Decorsiere, A., Mueller, H., van Breugel, P. C., Abdul, F., Gerossier, L., Beran, R. K., Livingston, C. M., Niu, C., Fletcher, S. P., Hantz, O., Strubin, M. Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor. Nature 531: 386-389, 2016. 2. Torres-Rosell, J., Machin, F., Farmer, S., Jarmuz, A., Eydmann, T., Dalgaard, J. Z., Aragon, L.SMC5 and SMC6 genes are required for the segregation of repetitive chromosome regions.Nature Cell Biol. 7: 412-419, 2005.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu SMC6

Target: SMC6 (SMC6 Structural Maintenance of Chromosomes 6-Like 1 (SMC6))

Andere Bezeichnung: SMC6

Hintergrund:

Synonyms: Structural maintenance of chromosomes protein 6, SMC protein 6, SMC-6, hSMC6, SMC6, SMC6L1

Tissue Specificity: Widely expressed (PubMed:11408570). Strongly expressed in testis (PubMed:11408570).

Background: Structural maintenance of chromosomes protein 6 is a protein that in humans is encoded by the SMC6 gene. Structural maintenance of chromosomes protein 6, also knowns SMC6L1, is a protein that in humans is encoded by the SMC6 gene. It is involved in the Alternative lengthening of telomeres cancer mechanism. The International Radiation Hybrid Mapping Consortium mapped the SMC6L1 gene to chromosome 2.

Molekulargewicht: 130 kDa

Gen-ID: 79677