MCF2 Antikörper (AA 42-925)

Produktnummer ABIN7601702

Dieses Anti-MCF2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MCF2 in WB, ELISA und FACS. Geeignet für Human.

Kurzübersicht für MCF2 Antikörper (AA 42-925) (ABIN7601702)

Target: MCF2 (MCF.2 Cell Line Derived Transforming Sequence (MCF2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-MCF2 Antikörper

Bindungsspezifität: AA 42-925

Verwendungszweck: Anti-DBL Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-DBL Antibody Picoband® (ABIN7601702). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human DBL recombinant protein (Position: D42-Y925).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Anson, D. S., Blake, D. J., Winship, P. R., Birnbaum, D., Brownlee, G. G. Nullisomic deletion of the mcf.2 transforming gene in two haemophilia B patients. EMBO J. 7: 2795-2799, 1988. 2. Eva, A., Aaronson, S. A. Isolation of a new human oncogene from a diffuse B-cell lymphoma. Nature 316: 273-275, 1985. 3. Eva, A., Vecchio, G., Rao, C. D., Tronick, S. R., Aaronson, S. A. The predicted DBL oncogene product defines a distinct class of transforming proteins. Proc. Nat. Acad. Sci. 85: 2061-2065, 1988.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu MCF2

Target: MCF2 (MCF.2 Cell Line Derived Transforming Sequence (MCF2))

Andere Bezeichnung: MCF2

Hintergrund:

Synonyms: Protein phosphatase 1 regulatory subunit 14A,17 kDa PKC-potentiated inhibitory protein of PP1,Protein kinase C-potentiated inhibitor protein of 17 kDa,CPI-17,PPP1R14A,CPI17, PPP1INL,

Tissue Specificity: Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta. .

Background: The DBL proto-oncogene is a protein that in humans is encoded by the MCF2 gene. The oncogenic protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that exerts control over some members of the Rho family of small GTPases. Several transcript variants encoding different isoforms have been found for this gene. These isoforms exhibit different expression patterns and varying levels of GEF activity.

Molekulargewicht: 125 kDa

Gen-ID: 4168

UniProt: P10911