MCF2 Antikörper (AA 705-925)

Produktnummer ABIN7166480

Produktdetails anti-MCF2 Antikörper

Target: MCF2 (MCF.2 Cell Line Derived Transforming Sequence (MCF2))

Bindungsspezifität: AA 705-925

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCF2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Proto-oncogene DBL protein (705-925AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MCF2

Target: MCF2 (MCF.2 Cell Line Derived Transforming Sequence (MCF2))

Andere Bezeichnung: MCF2 (MCF2 Produkte)

Synonyme: ARHGEF21 antikoerper, DBL antikoerper, MCF.2 cell line derived transforming sequence antikoerper, MCF2 antikoerper

Hintergrund:

Background: Guanine nucleotide exchange factor (GEF) that modulates the Rho family of GTPases. Promotes the conversion of some member of the Rho family GTPase from the GDP-bound to the GTP-bound form. Isoform 1 exhibits no activity toward RHOA, RAC1 or CDC42. Isoform 2 exhibits decreased GEF activity toward CDC42. Isoform 3 exhibits a weak but significant activity toward RAC1 and CDC42. Isoform 4 exhibits significant activity toward RHOA and CDC42. The truncated DBL oncogene is active toward RHOA, RAC1 and CDC42.

Aliases: MCF2 antibody, DBLProto-oncogene DBL antibody, Proto-oncogene MCF-2) [Cleaved into: MCF2-transforming protein, DBL-transforming protein] antibody

UniProt: P10911