MNT Antikörper (AA 381-564)

Produktnummer ABIN7601555

Dieser Anti-MNT Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von MNT in WB, ELISA, ICC, IF und IHC. Geeignet für Human.

Kurzübersicht für MNT Antikörper (AA 381-564) (ABIN7601555)

Target: MNT (MNT, MAX Dimerization Protein (MNT))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MNT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)

Produktdetails anti-MNT Antikörper

Bindungsspezifität: AA 381-564

Verwendungszweck: Anti-MNT Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-MNT Antibody (ABIN7601555). Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human MNT recombinant protein (Position: H381-N564).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu MNT

Target: MNT (MNT, MAX Dimerization Protein (MNT))

Andere Bezeichnung: MNT

Hintergrund:

Synonyms: Max-binding protein MNT, Class D basic helix-loop-helix protein 3, bHLHd3, Myc antagonist MNT, Protein ROX, MNT, BHLHD3, ROX

Tissue Specificity: Expressed in some normal epithelial tissues and in some carcinoma cell lines.

Background: MNT (Max's Next Tango) is a Max-binding protein that is encoded by the MNT gene. It is mapped to 17p13.3. The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.

Molekulargewicht: 62 kDa

Gen-ID: 4335

UniProt: Q99583

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation