MNT Antikörper (N-Term)

Produktnummer ABIN2781100

Der Kaninchen Polyklonal anti-MNT Antikörper (ABIN2781100) detektiert spezifisch MNT in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Pferd, Schwein und Saccharomyces cerevisiae.

Kurzübersicht für MNT Antikörper (N-Term) (ABIN2781100)

Target: MNT (MNT, MAX Dimerization Protein (MNT))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Pferd, Schwein, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MNT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MNT Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: MNT Antibody - N-terminal region

Sequenz: SIETLLEAAR FLEWQAQQQQ RAREEQERLR LEQEREQEQK KANSLARLAH

Homologie: Cow: 93%, Dog: 93%, Horse: 80%, Human: 100%, Mouse: 93%, Pig: 80%, Rabbit: 93%, Rat: 93%, Yeast: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against MNT. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MNT

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39412-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu MNT

Target: MNT (MNT, MAX Dimerization Protein (MNT))

Andere Bezeichnung: MNT

Hintergrund:

Background Information: The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. MNT is a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: MAX binding protein

Alternative Symbols: ROX, MAD6, MXD6, bHLHd3, lncRNA-HAL

Protein Name: Max-binding protein MNT

Molekulargewicht: 62kDa

Gen-ID: 4335

NCBI Accession: NP_064706

UniProt: Q99583

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation