TNIP1 Antikörper (AA 312-371)

Produktnummer ABIN7601284

Der Kaninchen Polyklonal Anti-TNIP1-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, TNIP1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für TNIP1 Antikörper (AA 312-371) (ABIN7601284)

Target: TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TNIP1 Antikörper

Bindungsspezifität: AA 312-371

Verwendungszweck: Anti-TNIP1 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-TNIP1 Antibody Picoband® (ABIN7601284). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human TNIP1 recombinant protein (Position: E312-K371).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. El Bakkouri, K., Wullaert, A., Haegman, M., Heyninck, K., Beyaert, R. Adenoviral gene transfer of the NK-kappa-B inhibitory protein ABIN-1 decreases allergic airway inflammation in a murine asthma model. J. Biol. Chem. 280: 17938-17944, 2005. 2. Fukushi, M., Dixon, J., Kimura, T., Tsurutani, N., Dixon, M. J., Yamamoto, N. Identification and cloning of a novel cellular protein Naf1, Nef-associated factor 1, that increases cell surface CD4 expression. FEBS Lett. 442: 83-88, 1999. 3. Oshima, S., Turer, E. E., Callahan, J. A., Chai, S., Advincula, R., Barrera, J., Shifrin, N., Lee, B., Yen, B., Woo, T., Malynn, B. A., Ma, A. ABIN-1 is a ubiquitin sensor that restricts cell death and sustains embryonic development. Nature 457: 906-909, 2009. Note: Erratum: Nature 458: 538 only, 2009.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu TNIP1

Target: TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))

Andere Bezeichnung: TNIP1

Hintergrund:

Synonyms: Tumor necrosis factor receptor superfamily member 14,Herpes virus entry mediator A,Herpesvirus entry mediator A,HveA,Tumor necrosis factor receptor-like 2,TR2,CD270,TNFRSF14,HVEA, HVEM,UNQ329/PRO509,

Tissue Specificity: Widely expressed, with the highest expression in lung, spleen and thymus.

Background: TNFAIP3-interacting protein 1 is a protein that in humans is encoded by the TNIP1 gene. This gene encodes an A20-binding protein which plays a role in autoimmunity and tissue homeostasis through the regulation of nuclear factor kappa-B activation. Mutations in this gene have been associated with psoriatic arthritis, rheumatoid arthritis, and systemic lupus erythematosus. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 80-85 kDa

Gen-ID: 10318

UniProt: Q15025

Pathways: Activation of Innate immune Response