PHF21B Antikörper (AA 291-499)

Produktnummer ABIN7601150

Produktdetails anti-PHF21B Antikörper

Target: PHF21B (PHD Finger Protein 21B (PHF21B))

Bindungsspezifität: AA 291-499

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHF21B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)

Verwendungszweck: Anti-PHF21B Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-PHF21B Antibody Picoband® (ABIN7601150). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PHF21B recombinant protein (Position: E291-M499).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bergamo, N. A., da Silva Veiga, L. C., dos Reis, P. P., Nishimoto, I. N., Magrin, J., Kowalski, L. P., Squire, J. A., Rogatto, S. R. Classic and molecular cytogenetic analyses reveal chromosomal gains and losses correlated with survival in head and neck cancer patients. Clin. Cancer Res. 11: 621-631, 2005. 2. Bertonha, F. B., Barros Filho, M. deC., Kuasne, H., dos Reis, P. P., da Costa Prando, E., Munoz, J. J. A. M., Roffe, M., Hajj, G. N. M., Kowalski, L. P., Rainho, C. A., Rogatto, S. R. PHF21B as a candidate tumor suppressor gene in head and neck squamous cell carcinomas. Molec. Oncol. 9: 450-462, 2015. 3. Reis, P. P., Rogatto, S. R., Kowalski, L. P., Nishimoto, I. N., Montovani, J. C., Corpus, G., Squire, J. A., Kamel-Reid, S. Quantitative real-time PCR identifies a critical region of deletion on 22q13 related to prognosis in oral cancer. Oncogene 21: 6480-6487, 2002.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu PHF21B

Target: PHF21B (PHD Finger Protein 21B (PHF21B))

Andere Bezeichnung: PHF21B (PHF21B Produkte)

Hintergrund:

Synonyms: Kelch repeat and BTB domain-containing protein 2, BTB and kelch domain-containing protein 1, KBTBD2, BKLHD1, KIAA1489

Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Background: PHF21B (PHD finger protein 21B), also known as PHF4, is a 531 amino acid protein that contains one PHD-type zinc finger and is expressed as multiple alternatively spliced isoforms. The gene encoding PHF21B maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, neurofibromatosis type 2, autism and schizophrenia.

Molekulargewicht: 57 kDa

Gen-ID: 112885