ARHGEF7 Antikörper (AA 25-637)

Produktnummer ABIN7600917

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ARHGEF7 in WB, ELISA, IHC, IF, ICC und FACS. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.

Kurzübersicht für ARHGEF7 Antikörper (AA 25-637) (ABIN7600917)

Target: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Produktdetails anti-ARHGEF7 Antikörper

Bindungsspezifität: AA 25-637

Verwendungszweck: Anti-ARHGEF7 Antibody

Homologie: Human ARHGEF7 shares 90.4% amino acid (aa) sequence identity with mouse ARHGEF7.

Produktmerkmale: Anti-ARHGEF7 Antibody. Tested in WB, IHC, ICC/IF, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human ARHGEF7 recombinant protein (Position: S25-N637). Human ARHGEF7 shares 90.4% amino acid (aa) sequence identity with mouse ARHGEF7.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu ARHGEF7

Target: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Andere Bezeichnung: ARHGEF7

Hintergrund:

Background: Rho guanine nucleotide exchange factor 7 is a protein that in humans is encoded by the ARHGEF7 gene. This gene encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene.

Gene Full Name: Rho guanine nucleotide exchange factor 7

Molekulargewicht: 80 kDa

Gen-ID: 8874

UniProt: Q14155

Pathways: EGFR Signaling Pathway, Neurotrophin Signalübertragung, EGFR Downregulation