CA4 Antikörper (AA 25-291)

Produktnummer ABIN7600898

Dieses Anti-CA4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CA4 in WB, IHC, ELISA und FACS. Geeignet für Maus und Ratte.

Kurzübersicht für CA4 Antikörper (AA 25-291) (ABIN7600898)

Target: CA4 (Carbonic Anhydrase IV (CA4))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Produktdetails anti-CA4 Antikörper

Bindungsspezifität: AA 25-291

Verwendungszweck: Anti-Carbonic Anhydrase 4/CA4 Picoband® Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Carbonic Anhydrase 4/CA4 Picoband® Antibody (ABIN7600898). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Carbonic Anhydrase 4/CA4 recombinant protein (Position: E25-L291).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Alvarez, B. V., Vithana, E. N., Yang, Z., Koh, A. H., Yeung, K., Yong, V., Shandro, H. J., Chen, Y., Kolatkar, P., Palasingam, P., Zhang, K., Aung, T., Casey, J. R. Identification and characterization of a novel mutation in the carbonic anhydrase IV gene that causes retinitis pigmentosa. Invest. Ophthal. Vis. Sci. 48: 3459-3468, 2007. 2. Bardien, S., Ebenezer, N., Greenberg, J., Inglehearn, C. F., Bartmann, L., Goliath, R., Beighton, P., Ramesar, R., Bhattacharya, S. S. An eighth locus for autosomal dominant retinitis pigmentosa is linked to chromosome 17q. Hum. Molec. Genet. 4: 1459-1462, 1995. 3. Bardien, S., Ramesar, R., Bhattacharya, S., Greenberg, J. Retinitis pigmentosa locus on 17q (RP17): fine localization to 17q22 and exclusion of the PDEG and TIMP2 genes. Hum. Genet. 101: 13-17, 1997.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu CA4

Target: CA4 (Carbonic Anhydrase IV (CA4))

Andere Bezeichnung: Ca4

Hintergrund:

Synonyms: Carbonic anhydrase 4, Carbonate dehydratase IV, Carbonic anhydrase IV, CA-IV, Ca4, Car4

Tissue Specificity: Expressed in the endothelium of the choriocapillaris in eyes (at protein level). Not expressed in the retinal epithelium at detectable levels. .

Background: Carbonic anhydrase 4 is an enzyme that in humans is encoded by the CA4 gene. It is mapped to 11, 11 C. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Its exact function is not known, however, it may have a role in inherited renal abnormalities of bicarbonate transport.

Molekulargewicht: 35 kDa

Gen-ID: 12351

UniProt: Q64444