NFIX Antikörper (AA 246-410)

Produktnummer ABIN7600873

Der Kaninchen Polyklonal Anti-NFIX-Antikörper wurde für WB, ELISA, ICC, IF und FACS validiert. Er ist geeignet, NFIX in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für NFIX Antikörper (AA 246-410) (ABIN7600873)

Target: NFIX (MLZE) (Nuclear Factor I/X (MLZE))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFIX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-NFIX Antikörper

Bindungsspezifität: AA 246-410

Verwendungszweck: Anti-NFIX Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-NFIX Antibody Picoband® (ABIN7600873). Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human NFIX recombinant protein (Position: A246-D410).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Adam, M. P., Hennekam, R. C. M., Keppen, L. D., Bull, M. J., Clericuzio, C. L., Burke, L. W., Ormond, K. E., Hoyme, H. E. Marshall-Smith syndrome: natural history and evidence of an osteochondrodysplasia with connective tissue abnormalities. Am. J. Med. Genet. 137A: 117-124, 2005. 2. Campbell, C. E., Piper, M., Plachez, C., Yeh, Y.-T., Baizer, J. S., Osinski, J. M., Litwack, E. D., Richards, L. J., Gronostajski, R. M. The transcription factor Nfix is essential for normal brain development. BMC Dev. Biol. 8: 52, 2008. Note: Electronic Article. 3. Dernedde, G., Pendeville, P., Veyckemans, F., Verellen, G., Gillerot, Y. Anaesthetic management of a child with Marshall-Smith syndrome. Can. J. Anaesth. 45: 660-663, 1998.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu NFIX

Target: NFIX (MLZE) (Nuclear Factor I/X (MLZE))

Andere Bezeichnung: NFIX

Hintergrund:

Synonyms: Prostaglandin E synthase 3, Cytosolic prostaglandin E2 synthase, Cpges, Hsp90 co-chaperone, Progesterone receptor complex p23, Telomerase-binding protein p23, PTGES3, P23, TEBP

Tissue Specificity: Mainly expressed in testis. Isoform 3 is expressed predominantly in adult testis, weakly in pancreas, embryonic testis and sperm, and at very low levels in other organs.

Background: Nuclear factor 1 X-type is a protein that in humans is encoded by the NFIX gene. The protein encoded by this gene is a transcription factor that binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3 in viral and cellular promoters. The encoded protein can also stimulate adenovirus replication in vitro. Three transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 55 kDa

Gen-ID: 4784

UniProt: Q14938

Pathways: Skeletal Muscle Fiber Development