TUBGCP2 Antikörper (AA 213-888)

Produktnummer ABIN7600646

Produktdetails anti-TUBGCP2 Antikörper

Target: TUBGCP2 (Tubulin, gamma Complex Associated Protein 2 (TUBGCP2))

Bindungsspezifität: AA 213-888

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TUBGCP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Verwendungszweck: Anti-TUBGCP2 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-TUBGCP2 Antibody Picoband® (ABIN7600646). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human TUBGCP2 recombinant protein (Position: Q213-R888).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hartz, P. A. Personal Communication. Baltimore, Md. 12/18/2017. 2. Mitani, T., Punetha, J., Akalin, I., Pehlivan, D., Dawidziuk, M., Akdemir, Z. C., Yilmaz, S., Aslan, E., Hunter, J. V., Hijazi, H., Grochowski, C. M., Jhangiani, S. N., and 25 others. Bi-allelic pathogenic variants in TUBGCP2 cause microcephaly and lissencephaly spectrum disorders. Am. J. Hum. Genet. 105: 1005-1015, 2019. 3. Murphy, S. M., Urbani, L., Stearns, T. The mammalian gamma-tubulin complex contains homologues of the yeast spindle pole body components Spc97p and Spc98p. J. Cell Biol. 141: 663-674, 1998.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu TUBGCP2

Target: TUBGCP2 (Tubulin, gamma Complex Associated Protein 2 (TUBGCP2))

Andere Bezeichnung: TUBGCP2 (TUBGCP2 Produkte)

Hintergrund:

Synonyms: Neutrophil defensin 1,Defensin, alpha 1,HNP-1,HP-1,HP1,HP 1-56,Neutrophil defensin 2,HNP-2,HP-2,HP2,DEFA1,DEF1, DEFA2, MRS,DEFA1B,

Tissue Specificity: Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow.

Background: Gamma-tubulin complex component 2 is a protein that in humans is encoded by the TUBGCP2 gene. It is part of the gamma tubulin complex, which required formicrotubule nucleation at the centrosome. Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome. Gamma-tubulin complex is composed of gamma-tubulin, TUBGCP2, TUBGCP3, TUBGCP4, TUBGCP5 and TUBGCP6.

Molekulargewicht: 103 kDa

Gen-ID: 10844

Pathways: M Phase, SARS-CoV-2 Protein Interaktom