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HMOX1 Antikörper (AA 2-261)

Der Kaninchen Polyklonal Anti-HMOX1-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, HMOX1 in Proben von Ratte zu detektieren.
Produktnummer ABIN7600483

Kurzübersicht für HMOX1 Antikörper (AA 2-261) (ABIN7600483)

Target

Alle HMOX1 Antikörper anzeigen
HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

Reaktivität

  • 116
  • 55
  • 42
  • 18
  • 11
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Ratte

Wirt

  • 129
  • 48
  • 2
  • 1
  • 1
Kaninchen

Klonalität

  • 124
  • 57
Polyklonal

Konjugat

  • 92
  • 23
  • 16
  • 7
  • 7
  • 7
  • 5
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser HMOX1 Antikörper ist unkonjugiert

Applikation

  • 153
  • 102
  • 75
  • 58
  • 54
  • 50
  • 18
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA
  • Bindungsspezifität

    • 13
    • 11
    • 9
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-261

    Verwendungszweck

    Anti-Heme Oxygenase 1/Hmox1 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-Heme Oxygenase 1/Hmox1 Antibody Picoband® (ABIN7600483). Tested in ELISA, WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived rat Heme Oxygenase 1/Hmox1 recombinant protein (Position: E2-T261).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL/mL, Rat
    ELISA, 0.1-0.5 μg/mL/mL, Rat
    1. He, C. H., Gong, P., Hu, B., Stewart, D., Choi, M. E., Choi, A. M. K., Alam, J.Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein: implication for heme oxygenase-1 gene regulation. J. Biol. Chem. 276: 20858-20865, 2001. 2. Piantadosi CA, Withers CM, Bartz RR, MacGarvey NC, Fu P, Sweeney TE, Welty-Wolf KE, Suliman HB (May 2011). "Heme oxygenase-1 couples activation of mitochondrial biogenesis to anti-inflammatory cytokine expression". J. Biol. Chem.286 (18): 16374-85.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

    Andere Bezeichnung

    Hmox1

    Hintergrund

    Synonyms: Angiotensin-converting enzyme, ACE, Dipeptidyl carboxypeptidase I, Kininase II, CD143, Angiotensin-converting enzyme, soluble form, Ace, Dcp1

    Tissue Specificity: Testis-specific isoform is expressed in spermatocytes, adult testis.

    Background: HMOX1 (heme oxygenase (decycling) 1), also known as HO-1, is a human gene that encodes for the enzyme heme oxygenase 1. It is an essential enzyme in heme catabolism, it cleaves heme to form biliverdin. HMOX1 belongs to the heme oxygenase family. The HMOX1 gene is located on the long (q) arm of chromosome 22 at position 12.3, from base pair 34,101,636 to base pair 34,114,748. HMOX1, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. HMOX1 activity is induced by its substrate heme and by various nonheme substances.

    Molekulargewicht

    33 kDa

    Gen-ID

    24451

    UniProt

    P06762

    Pathways

    Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interaktom
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