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VRK2 Antikörper (AA 19-491)

Der Kaninchen Polyklonal Anti-VRK2-Antikörper wurde für WB, ELISA und FACS validiert. Er ist geeignet, VRK2 in Proben von Human zu detektieren.
Produktnummer ABIN7600420

Kurzübersicht für VRK2 Antikörper (AA 19-491) (ABIN7600420)

Target

Alle VRK2 Antikörper anzeigen
VRK2 (Vaccinia Related Kinase 2 (VRK2))

Reaktivität

  • 28
  • 20
  • 1
Human

Wirt

  • 41
  • 2
  • 1
Kaninchen

Klonalität

  • 43
  • 1
Polyklonal

Konjugat

  • 16
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser VRK2 Antikörper ist unkonjugiert

Applikation

  • 34
  • 20
  • 13
  • 13
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • Bindungsspezifität

    • 15
    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 19-491

    Verwendungszweck

    Anti-VRK2 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-VRK2 Antibody Picoband® (ABIN7600420). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human VRK2 recombinant protein (Position: K19-R491).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Nezu, J., Oku, A., Jones, M. H., Shimane, M. Identification of two novel human putative serine/threonine kinases, VRK1 and VRK2, with structural similarity to vaccinia virus B1R kinase. Genomics 45: 327-331, 1997.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    VRK2 (Vaccinia Related Kinase 2 (VRK2))

    Andere Bezeichnung

    VRK2

    Hintergrund

    Synonyms: NACHT, LRR and PYD domains-containing protein 2, Nucleotide-binding site protein 1, PYRIN domain and NACHT domain-containing protein 1, PYRIN-containing APAF1-like protein 2, NLRP2, NALP2, NBS1, PAN1, PYPAF2

    Tissue Specificity: Expressed at high levels in lung, placenta and thymus and at lower levels in ovary, intestine and brain.

    Background: Serine/threonine-protein kinase VRK2 is an enzyme that in humans is encoded by the VRK2 gene. This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. The encoded protein acts as an effector of signaling pathways that regulate apoptosis and tumor cell growth. Variants in this gene have been associated with schizophrenia. Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity.

    Molekulargewicht

    50 kDa

    Gen-ID

    7444

    UniProt

    Q86Y07
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