SMCR7L Antikörper (AA 189-463)

Produktnummer ABIN7600396

Der Kaninchen Polyklonal Anti-SMCR7L-Antikörper wurde für WB, ELISA, IF, IHC, ICC und FACS validiert. Er ist geeignet, SMCR7L in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für SMCR7L Antikörper (AA 189-463) (ABIN7600396)

Target: SMCR7L (Smith-Magenis Syndrome Chromosome Region, Candidate 7-Like (SMCR7L))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMCR7L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Produktdetails anti-SMCR7L Antikörper

Bindungsspezifität: AA 189-463

Verwendungszweck: Anti-MIEF1 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-MIEF1 Antibody Picoband® (ABIN7600396). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human MIEF1 recombinant protein (Position: S189-T463).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hartz, P. A. Personal Communication. Baltimore, Md. 10/25/2013. 2. Palmer, C. S., Elgass, K. D., Parton, R. G., Osellame, L. D., Stojanovski, D., Ryan, M. T. Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission. J. Biol. Chem. 288: 27584-27593, 2013. 3. Palmer, C. S., Osellame, L. D., Laine, D., Koutsopoulos, O. S., Frazier, A. E., Ryan, M. T. MiD49 and MiD51, new components of the mitochondrial fission machinery. EMBO Rep. 12: 565-573, 2011.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu SMCR7L

Target: SMCR7L (Smith-Magenis Syndrome Chromosome Region, Candidate 7-Like (SMCR7L))

Andere Bezeichnung: MIEF1

Hintergrund:

Synonyms: Disintegrin and metalloproteinase domain-containing protein 28,ADAM 28,3.4.24.-,Epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II,eMDC II,Metalloproteinase-like, disintegrin-like, and cysteine-rich protein L,MDC-L,ADAM28,ADAM23, MDCL,

Tissue Specificity: Expressed predominantly in secondary lymphoid tissues, such as lymph node, spleen, small intestine, stomach, colon, appendix and trachea. The lymphocyte population is responsible for expression of this protein in these tissues. Isoform 2 is expressed preferentially in spleen.

Background: Mitochondrial dynamic protein MID51 (MID51) also known as mitochondrial elongation factor 1 (MIEF1) or Smith-Magenis syndrome chromosome region candidate gene 7 protein-like (SMCR7L) is a protein that in humans is encoded by the SMCR7L gene. The SMCR7L gene codes for a protein that has been called MiD51/MIEF1 and shown to regulate mitochondrial fission by interacting with the proteins Drp1 and FIS1.

Molekulargewicht: 51 kDa

Gen-ID: 54471