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SMCR7L Antikörper (Internal Region)

SMCR7L Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6265187
  • Target Alle SMCR7L Antikörper anzeigen
    SMCR7L (Smith-Magenis Syndrome Chromosome Region, Candidate 7-Like (SMCR7L))
    Bindungsspezifität
    • 15
    • 8
    • 8
    • 6
    • 6
    • 1
    Internal Region
    Reaktivität
    • 27
    • 24
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 39
    Kaninchen
    Klonalität
    • 39
    Polyklonal
    Konjugat
    • 11
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SMCR7L Antikörper ist unkonjugiert
    Applikation
    • 35
    • 22
    • 13
    • 13
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    SMCR7L/MID51 Antibody detects endogenous levels of total SMCR7L/MID51.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human SMCR7L/MID51, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product SMCR7L Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    SMCR7L (Smith-Magenis Syndrome Chromosome Region, Candidate 7-Like (SMCR7L))
    Andere Bezeichnung
    MIEF1 (SMCR7L Produkte)
    Synonyme
    MGC115280 antikoerper, HSU79252 antikoerper, MID51 antikoerper, MIEF1 antikoerper, dJ1104E15.3 antikoerper, A230016E22 antikoerper, AI452372 antikoerper, im:7156228 antikoerper, smcr7l antikoerper, zgc:162279 antikoerper, mitochondrial elongation factor 1 antikoerper, mitochondrial elongation factor 1 S homeolog antikoerper, MIEF1 antikoerper, mief1.S antikoerper, Mief1 antikoerper, mief1 antikoerper
    Hintergrund

    Description: Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADP to stimulate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubules with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP. Does not require ADP for its function in recruiting DNM1L.

    Gene: MIEF1

    Molekulargewicht
    48-51 kDa
    Gen-ID
    54471
    UniProt
    Q9NQG6
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