PIPOX Antikörper (AA 173-390)

Produktnummer ABIN7600291

Der Kaninchen Polyklonal Anti-PIPOX-Antikörper wurde für ELISA, WB und IHC validiert. Er ist geeignet, PIPOX in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für PIPOX Antikörper (AA 173-390) (ABIN7600291)

Target: PIPOX (Pipecolic Acid Oxidase (PIPOX))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIPOX Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PIPOX Antikörper

Bindungsspezifität: AA 173-390

Verwendungszweck: Anti-PIPOX Antibody Picoband®

Produktmerkmale: Anti-PIPOX Antibody Picoband® (ABIN7600291). Tested in WB, IHC, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PIPOX recombinant protein (Position: E173-L390). Human PIPOX shares 81.2% amino acid (aa) sequence identity with mouse PIPOX.

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Dodt, G., Kim, D., Reimann, S., McCabe, K., Gould, S. J., Mihalik, S. J. The human L-pipecolic acid oxidase is similar to bacterial monomeric sarcosine oxidases rather than D-amino acid oxidases. Cell Biochem. Biophys. 32: 313-316, 2000. 2. Dodt, G., Kim, D. G., Reimann, S. A., Reuber, B. E., McCabe, K., Gould, S. J., Mihalik, S. J. L-pipecolic acid oxidase, a human enzyme essential for the degradation of L-pipecolic acid, is most similar to the monomeric sarcosine oxidases. Biochem. J. 345: 487-494, 2000. 3. IJlst, L., de Kromme, I., Oostheim, W., Wanders, R. J. A. Molecular cloning and expression of human L-pipecolate oxidase. Biochem. Biophys. Res. Commun. 270: 1101-1105, 2000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu PIPOX

Target: PIPOX (Pipecolic Acid Oxidase (PIPOX))

Andere Bezeichnung: PIPOX

Hintergrund: PIPOX (Pipecolic Acid And Sarcosine Oxidase, also known as L-pipecolate oxidase) is a Protein Coding gene. The PIPOX gene, located on 17q11.2, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, C.elegans, S.pombe, N.crassa, A.thaliana, rice, and frog. This enzyme oxidizes L-pipecolic acid with the concomitant production of H2O2 in the peroxisome of the normal human liver. Pipecolate, an intermediate of the lysine catabolic pathway, is oxidized to Δ1 -piperideine-6-carboxylate (P6C) by the PIPOX. Diseases associated with PIPOX include Inflammatory Bowel Disease 15 and Zellweger Syndrome. Among its related pathways are Lysine degradation and Viral mRNA Translation. 215 organisms have orthologs with the human gene PIPOX.

Molekulargewicht: 40 kDa

Gen-ID: 51268

UniProt: Q9P0Z9