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ARHGEF5 Antikörper (AA 1555-1597)

Der Kaninchen Polyklonal Anti-ARHGEF5-Antikörper wurde für WB, ELISA und FACS validiert. Er ist geeignet, ARHGEF5 in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN7600152

Kurzübersicht für ARHGEF5 Antikörper (AA 1555-1597) (ABIN7600152)

Target

Alle ARHGEF5 Antikörper anzeigen
ARHGEF5 (rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5))

Reaktivität

  • 45
  • 17
  • 8
  • 1
Human, Maus, Ratte

Wirt

  • 41
  • 3
  • 2
  • 1
Kaninchen

Klonalität

  • 43
  • 4
Polyklonal

Konjugat

  • 30
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ARHGEF5 Antikörper ist unkonjugiert

Applikation

  • 31
  • 21
  • 12
  • 6
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • Bindungsspezifität

    • 8
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1555-1597

    Verwendungszweck

    Anti-ARHGEF5 Antibody Picoband®

    Produktmerkmale

    Anti-ARHGEF5 Antibody Picoband® (ABIN7600152). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human ARHGEF5 recombinant protein (Position: D1555-A1597). Human ARHGEF5 shares 97.6% amino acid (aa) sequence identity with mouse ARHGEF5.
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. Chan, A. M-L., McGovern, E. S., Catalano, G., Fleming, T. P., Miki, T. Expression cDNA cloning of a novel oncogene with sequence similarity to regulators of small GTP-binding proteins. Oncogene 9: 1057-1063, 1994. 2. Debily, M.-A., Camarca, A., Ciullo, M., Mayer, C., El Marhomy, S., Ba, I., Jalil, A., Anzisi, A., Guardiola, J., Piatier-Tonneau, D. Expression and molecular characterization of alternative transcripts of the ARHGEF5/TIM oncogene specific for human breast cancer. Hum. Molec. Genet. 13: 323-334, 2004. 3. Miki, T., Fleming, T. P., Crescenzi, M., Molloy, C. J., Blam, S. B., Reynolds, S. H., Aaronson, S. A. Development of a highly efficient expression cDNA cloning system: application to oncogene isolation. Proc. Nat. Acad. Sci. 88: 5167-5171, 1991.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    ARHGEF5 (rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5))

    Andere Bezeichnung

    ARHGEF5

    Hintergrund

    Rho guanine nucleotide exchange factor 5 is a protein that in humans is encoded by the ARHGEF5 gene. Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization.

    Molekulargewicht

    250 kDa

    Gen-ID

    7984

    UniProt

    Q12774
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