ARHGEF5 Antikörper (AA 433-507)

Produktnummer ABIN7167986

Produktdetails anti-ARHGEF5 Antikörper

Target: ARHGEF5 (rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5))

Bindungsspezifität: AA 433-507

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF5 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Rho guanine nucleotide exchange factor 5 protein (433-507AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ARHGEF5

Target: ARHGEF5 (rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5))

Andere Bezeichnung: ARHGEF5 (ARHGEF5 Produkte)

Synonyme: ARHGEF5 antikoerper, GEF5 antikoerper, P60 antikoerper, TIM antikoerper, TIM1 antikoerper, 2210412D05Rik antikoerper, AA717842 antikoerper, AW495314 antikoerper, Tim1 antikoerper, Rho guanine nucleotide exchange factor 5 antikoerper, rho guanine nucleotide exchange factor 5 antikoerper, Rho guanine nucleotide exchange factor (GEF) 5 antikoerper, ARHGEF5 antikoerper, LOC100414419 antikoerper, Arhgef5 antikoerper

Hintergrund:

Background: Guanine nucleotide exchange factor which activates Rho GTPases (PubMed:15601624). Strongly activates RHOA (PubMed:15601624). Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1 (By similarity). Involved in regulation of cell shape and actin cytoskeletal organization (PubMed:15601624). Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia (PubMed:14662653). Required for SRC-induced podosome formation (By similarity). Involved in positive regulation of immature dendritic cell migration (By similarity).

Aliases: ARHG5_HUMAN antibody, ARHGEF 5 antibody, ARHGEF5 antibody, DKFZp686N1969 antibody, ephexin 3 antibody, Ephexin-3 antibody, GEF 5 antibody, GEF5 antibody, Guanine nucleotide regulatory protein TIM antibody, Oncogene TIM antibody, P60 antibody, p60 TIM antibody, Rho guanine nucleotide exchange factor (GEF) 5 antibody, Rho guanine nucleotide exchange factor 5 antibody, TIM 1 antibody, TIM antibody, TIM1 antibody, Transforming immortalized mammary oncogene antibody

UniProt: Q12774