SRRT Antikörper (AA 125-793)

Produktnummer ABIN7599883

Dieses Anti-SRRT-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SRRT in WB, ELISA, IHC, IP, IF, FACS und ICC. Geeignet für Human, Maus und Ratte.

Kurzübersicht für SRRT Antikörper (AA 125-793) (ABIN7599883)

Target: SRRT (Serrate RNA Effector Molecule Homolog (SRRT))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRRT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Produktdetails anti-SRRT Antikörper

Bindungsspezifität: AA 125-793

Verwendungszweck: Anti-ARS2/SRRT Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-ARS2/SRRT Antibody Picoband® (ABIN7599883). Tested in ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human ARS2/SRRT recombinant protein (Position: H125-Q793).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunoprecipitation, 0.5-2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Andreu-Agullo, C., Maurin, T., Thompson, C. B., Lai. E. C. Ars2 maintains neural stem-cell identity through transcriptional activation of Sox2. Nature 481: 195-198, 2011. 2. Gruber, J. J., Zatechka, D. S., Sabin, L. R., Yong, J., Lum, J. J., Kong, M., Zong, W.-X., Zhang, Z., Lau, C.-K., Rawlings, J., Cherry, S., Ihle, J. N., Dreyfuss, G., Thompson, C. B. Ars2 links nuclear cap-binding complex to RNA interference and cell proliferation. Cell 138: 328-339, 2009. 3. Kiriyama, M., Kobayashi, Y., Saito, M., Ishikawa, F., Yonehara, S. Interaction of FLASH with arsenite resistance protein 2 is involved in cell cycle progression at S phase. Molec. Cell. Biol. 29: 4729-4741, 2009.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu SRRT

Target: SRRT (Serrate RNA Effector Molecule Homolog (SRRT))

Andere Bezeichnung: SRRT

Hintergrund:

Synonyms: Cytochrome c oxidase subunit 4 isoform 1, mitochondrial, Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit IV isoform 1, COX IV-1, COX4I1, COX4

Tissue Specificity: Ubiquitous.

Background: Serrate RNA effector molecule homolog (SRRT) also known as arsenite-resistance protein 2 (ARS2) is a protein that in humans is encoded by the SRRT gene. Enables mRNA cap binding complex binding activity and protein-macromolecule adaptor activity. Involved in primary miRNA processing. Located in nucleoplasm. Part of ribonucleoprotein complex.

Molekulargewicht: 101 kDa

Gen-ID: 51593

Pathways: Notch Signalweg, Stem Cell Maintenance