SRRT Antikörper (AA 125-793)

Produktnummer ABIN7599883

Dieser Anti-SRRT Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von SRRT in WB, ELISA, IHC, IP, IF, FACS und ICC. Geeignet für Human, Maus und Ratte.

Kurzübersicht für SRRT Antikörper (AA 125-793) (ABIN7599883)

Target: SRRT (Serrate RNA Effector Molecule Homolog (SRRT))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRRT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Produktdetails anti-SRRT Antikörper

Bindungsspezifität: AA 125-793

Verwendungszweck: Anti-ARS2/SRRT Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-ARS2/SRRT Antibody Picoband® (ABIN7599883). Tested in ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human ARS2/SRRT recombinant protein (Position: H125-Q793).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunoprecipitation, 0.5-2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Andreu-Agullo, C., Maurin, T., Thompson, C. B., Lai. E. C. Ars2 maintains neural stem-cell identity through transcriptional activation of Sox2. Nature 481: 195-198, 2011. 2. Gruber, J. J., Zatechka, D. S., Sabin, L. R., Yong, J., Lum, J. J., Kong, M., Zong, W.-X., Zhang, Z., Lau, C.-K., Rawlings, J., Cherry, S., Ihle, J. N., Dreyfuss, G., Thompson, C. B. Ars2 links nuclear cap-binding complex to RNA interference and cell proliferation. Cell 138: 328-339, 2009. 3. Kiriyama, M., Kobayashi, Y., Saito, M., Ishikawa, F., Yonehara, S. Interaction of FLASH with arsenite resistance protein 2 is involved in cell cycle progression at S phase. Molec. Cell. Biol. 29: 4729-4741, 2009.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu SRRT

Target: SRRT (Serrate RNA Effector Molecule Homolog (SRRT))

Andere Bezeichnung: SRRT

Hintergrund:

Synonyms: Cytochrome c oxidase subunit 4 isoform 1, mitochondrial, Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit IV isoform 1, COX IV-1, COX4I1, COX4

Tissue Specificity: Ubiquitous.

Background: Serrate RNA effector molecule homolog (SRRT) also known as arsenite-resistance protein 2 (ARS2) is a protein that in humans is encoded by the SRRT gene. Enables mRNA cap binding complex binding activity and protein-macromolecule adaptor activity. Involved in primary miRNA processing. Located in nucleoplasm. Part of ribonucleoprotein complex.

Molekulargewicht: 101 kDa

Gen-ID: 51593

Pathways: Notch Signalweg, Stem Cell Maintenance