SPATA5 Antikörper (AA 115-853)

Produktnummer ABIN7599767

Produktdetails anti-SPATA5 Antikörper

Target: SPATA5 (Spermatogenesis Associated 5 (SPATA5))

Bindungsspezifität: AA 115-853

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPATA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Verwendungszweck: Anti-SPATA5 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-SPATA5 Antibody Picoband® (ABIN7599767). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SPATA5 recombinant protein (Position: E115-Q853).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hartz, P. A. Personal Communication. Baltimore, Md. 4/19/2011. 2. Kurata, H., Terashima, H., Nakashima, M., Matsumura, W., Ohno, K., Saito, Y., Maegaki, Y., Kubota, M., Nanba, E., Saitsu, H., Matsumoto, N., Kato, M. Characterization of SPATA5-related encephalopathy in early childhood. Clin. Genet. 90: 437-444, 2016. 3. Liu, Y., Black, J., Kisiel, N., Kulesz-Martin, M. F. SPAF, a new AAA-protein specific to early spermatogenesis and malignant conversion. Oncogene 19: 1579-1588, 2000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu SPATA5

Target: SPATA5 (Spermatogenesis Associated 5 (SPATA5))

Andere Bezeichnung: SPATA5 (SPATA5 Produkte)

Hintergrund:

Synonyms: Rho-related GTP-binding protein Rho6,Rho family GTPase 1,Rnd1,RND1,RHO6,

Tissue Specificity: Mostly expressed in brain and liver.

Background: Spermatogenesis-associated protein 5 is a protein that in humans is encoded by the SPATA5 gene. This gene encodes a member of the ATPase associated with diverse activities family, whose members are defined by a highly conserved ATPase domain. Members of this family participate in diverse cellular processes that include membrane fusion, DNA replication, microtubule severing, and protein degradation. The protein encoded by this gene has a putative mitochondrial targeting sequence and has been proposed to function in maintenance of mitochondrial function and integrity during mouse spermatogenesis. Allelic variants in this gene have been associated with epilepsy, hearing loss, and cognitive disability syndrome. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 98 kDa

Gen-ID: 166378