Clusterin Antikörper (AA 108-320)
Kurzübersicht für Clusterin Antikörper (AA 108-320) (ABIN7599684)
Target
Alle Clusterin (CLU) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
 - AA 108-320
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Verwendungszweck
 - Anti-Clusterin/CLU Antibody Picoband®
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Kreuzreaktivität (Details)
 - No cross-reactivity with other proteins.
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Produktmerkmale
 - Anti-Clusterin/CLU Antibody Picoband® (ABIN7599684). Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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Aufreinigung
 - Immunogen affinity purified.
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Immunogen
 - E.coli-derived human Clusterin/CLU recombinant protein (Position: A108-Q320).
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Isotyp
 - IgG
 
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Applikationshinweise
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                        Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bertrand, P., Poirier, J., Oda, T., Finch, C. E., Pasinetti, G. M. Association of apolipoprotein E genotype with brain levels of apolipoprotein E and apolipoprotein J (clusterin) in Alzheimer disease. Molec. Brain Res. 33: 174-178, 1995. 2. Birkenmeier, E. H., Letts, V. A., Frankel, W. N., Magenheimer, B. S., Calvet, J. P. Sulfated glycoprotein-2 (Sgp-2) maps to mouse chromosome 14. Mammalian Genome 4: 131-132, 1993. Note: Erratum: Mammalian Genome 4: 238 only, 1993. 3. Chen, X., Halberg, R. B., Ehrhardt, W. M., Torrealba, J., Dove, W. F. Clusterin as a biomarker in murine and human intestinal neoplasia. Proc. Nat. Acad. Sci. 100: 9530-9535, 2003. - 
                                            
Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Format
 - Lyophilized
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Rekonstitution
 - Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Konzentration
 - 500 μg/mL
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Buffer
 - Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Lagerung
 - 4 °C,-20 °C
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Informationen zur Lagerung
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                        At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. 
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. 
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- Clusterin (CLU)
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Andere Bezeichnung
 - CLU
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Hintergrund
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Synonyms: Vesicle-fusing ATPase, N-ethylmaleimide-sensitive fusion protein, NEM-sensitive fusion protein, Vesicular-fusion protein NSF, NSF
Background: The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.
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Molekulargewicht
 - 70 kDa
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Gen-ID
 - 1191
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UniProt
 - P10909
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Pathways
 - Apoptose, Negative Regulation of intrinsic apoptotic Signaling
 
Target
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