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MCM9 Antikörper (AA 1-644)

Dieses Anti-MCM9-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MCM9 in ELISA, WB und FACS. Geeignet für Human.
Produktnummer ABIN7599513

Kurzübersicht für MCM9 Antikörper (AA 1-644) (ABIN7599513)

Target

Alle MCM9 Antikörper anzeigen
MCM9 (Minichromosome Maintenance Deficient 9 (MCM9))

Reaktivität

  • 21
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 20
  • 1
Kaninchen

Klonalität

  • 20
  • 1
Polyklonal

Konjugat

  • 11
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MCM9 Antikörper ist unkonjugiert

Applikation

ELISA, Western Blotting (WB), Flow Cytometry (FACS)
  • Bindungsspezifität

    • 9
    • 3
    • 2
    • 2
    AA 1-644

    Verwendungszweck

    Anti-MCM9 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-MCM9 Antibody Picoband® (ABIN7599513). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human MCM9 recombinant protein (Position: M1-L644). Human MCM9 shares 92.7% and 93% amino acid (aa) sequence identity with mouse and rat MCM9, respectively.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, Human
    1. Fauchereau, F., Shalev, S., Chervinsky, E., Beck-Fruchter, R., Legois, B., Fellous, M., Caburet, S., Veitia, R. A. A non-sense MCM9 mutation in a familial case of primary ovarian insufficiency. Clin. Genet. 89: 603-607, 2016. 2. Lutzmann, M., Grey, C., Traver, S., Ganier, O., Maya-Mendoza, A., Ranisavljevic, N., Bernex, F., Nishiyama, A., Montel, N., Gavois, E., Forichon, L., de Massy, B., Mechali, M. MCM8- and MCM9-deficient mice reveal gametogenesis defects and genome instability due to impaired homologous recombination. Molec. Cell 47: 523-534, 2012. 3. Lutzmann, M., Maiorano, D., Mechali, M. Identification of full genes and proteins of MCM9, a novel, vertebrate-specific member of the MCM2-8 protein family. Gene 362: 51-56, 2005.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    MCM9 (Minichromosome Maintenance Deficient 9 (MCM9))

    Andere Bezeichnung

    MCM9

    Hintergrund

    Synonyms: MCM9, C6orf61, MCMDC1, DNA helicase MCM9, hMCM9, EC 3.6.4.12, Mini-chromosome maintenance deficient domain-containing protein 1, Minichromosome maintenance 9

    Background: The protein encoded by this gene is a member of the mini-chromosome maintenance (MCM) protein family that are essential for the initiation of eukaryotic genome replication. Binding of this protein to chromatin has been shown to be a pre-requisite for recruiting the MCM2-7 helicase to DNA replication origins. This protein also binds, and is a positive regulator of, the chromatin licensing and DNA replication factor 1, CDT1.

    Molekulargewicht

    127 kDa

    Gen-ID

    254394
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