SKIL Antikörper (AA 1-504)

Produktnummer ABIN7599455

Der Kaninchen Polyklonal anti-SKIL Antikörper wird verwendet zum Nachweis von SKIL in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IHC, IF, FACS und ICC.

Kurzübersicht für SKIL Antikörper (AA 1-504) (ABIN7599455)

Target: SKIL (SKI-Like Oncogene (SKIL))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SKIL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Produktdetails anti-SKIL Antikörper

Bindungsspezifität: AA 1-504

Verwendungszweck: Anti-SnoN/SNO/SKIL Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-SnoN/SNO/SKIL Antibody. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SnoN/SNO/SKIL recombinant protein (Position: M1-V504).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu SKIL

Target: SKIL (SKI-Like Oncogene (SKIL))

Andere Bezeichnung: SKIL

Hintergrund:

Background: Ski-like protein is a protein that in humans is encoded by the SKIL gene. The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.

Gene Full Name: SKI like proto-oncogene

Molekulargewicht: 77 kDa

Gen-ID: 6498

UniProt: P12757

Pathways: Positive Regulation of Response to DNA Damage Stimulus