TOX Antikörper (AA 1-495)

Produktnummer ABIN7599443

Der Kaninchen Polyklonal Anti-TOX-Antikörper wurde für WB, ELISA, IHC und FACS validiert. Er ist geeignet, TOX in Proben von Human und Maus zu detektieren.

Kurzübersicht für TOX Antikörper (AA 1-495) (ABIN7599443)

Target: TOX (Thymus High Mobility Group Box Protein (TOX))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TOX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktdetails anti-TOX Antikörper

Bindungsspezifität: AA 1-495

Verwendungszweck: Anti-TOX Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-TOX Antibody Picoband® (ABIN7599443). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human TOX recombinant protein (Position: M1-S495).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Alfei, F., Kanev, K., Hofmann, M., Wu, M., Ghoneim, H. E., Roelli, P., Utzschneider, D. T., von Hoesslin, M., Cullen, J. G., Fan, Y., Eisenberg, V., Wohlleber, D., Steiger, K., Merkler, D., Delorenzi, M., Knolle, P. A., Cohen, C. J., Thimme, R., Youngblood, B., Zehn, D. TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection. Nature 571: 265-269, 2019. 2. Grant, A. V., El Baghdadi, J., Sabri, A., El Azbaoui, S., Alaoui-Tahiri, K., Rhorfi, I. A., Gharbaoui, Y., Abid, A., Benkirane, M., Raharimanga, V., Richard, V., Orlova, M., and 11 others. Age-dependent association between pulmonary tuberculosis and common TOX variants in the 8q12-13 linkage region. Am. J. Hum. Genet. 92: 407-414, 2013. 3. Gross, M. B. Personal Communication. Baltimore, Md. 5/7/2013.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu TOX

Target: TOX (Thymus High Mobility Group Box Protein (TOX))

Andere Bezeichnung: TOX

Hintergrund:

Synonyms: Serine/threonine-protein kinase LMTK3, Lemur tyrosine kinase 3, LMTK3, KIAA1883, TYKLM3

Background: Thymocyte selection-associated high mobility group box protein TOX is a protein that in humans is encoded by the TOX gene. The protein encoded by this gene contains a HMG box DNA binding domain. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. This protein may function to regulate T-cell development.

Molekulargewicht: 57 kDa

Gen-ID: 9760

UniProt: O94900