SHANK1 Antikörper (AA 101-200)

Produktnummer ABIN726335

Der Kaninchen Polyklonal Anti-SHANK1-Antikörper wurde für WB, ELISA, IF (cc), IF (p), IHC (fro) und IHC (p) validiert. Er ist geeignet, SHANK1 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für SHANK1 Antikörper (AA 101-200) (ABIN726335)

Target: SHANK1 (SH3 and Multiple Ankyrin Repeat Domains 1 (SHANK1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SHANK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SHANK1 Antikörper

Bindungsspezifität: AA 101-200

Homologie: Human,Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Shank1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-SHANK1 Antikörper (ABIN726335)

Zhang, Zheng, Wan, Shao, Liu, Zhang, Zhang: "The potential use of H102 peptide-loaded dual-functional nanoparticles in the treatment of Alzheimer's disease." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 192, pp. 317-24, (2014) (PubMed).

Details zu SHANK1

Target: SHANK1 (SH3 and Multiple Ankyrin Repeat Domains 1 (SHANK1))

Andere Bezeichnung: SHANK 1

Hintergrund:

Synonyms: SSTRIP, SPANK-1, synamon, SH3 and multiple ankyrin repeat domains protein 1, Shank1, Somatostatin receptor-interacting protein, SSTR-interacting protein

Background: Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction.

Gen-ID: 50944

UniProt: Q9Y566

Pathways: Synaptic Membrane, Maintenance of Protein Location