Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C,-80 °C
Informationen zur Lagerung
Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
Target
TOLLIP
(Toll Interacting Protein (TOLLIP))
Andere Bezeichnung
Tollip
Hintergrund
Toll interacting protein, also known as Tollip, is an inhibitory adaptor protein within the signaling pathwayof IL-1 and Toll-like receptors (TLR). The Toll-like receptors are essential transmembrane signalingreceptors of the innate immune system that alert the host to the presence of a microbial invader. Tolliprecruits IRAk1 to the IL-1 receptor complex and inhibits IRAk1 phosphorylation and kinase activity.