TOLLIP Antikörper (AA 86-163)

Produktnummer ABIN7172257

Produktdetails anti-TOLLIP Antikörper

Target: TOLLIP (Toll Interacting Protein (TOLLIP))

Bindungsspezifität: AA 86-163

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TOLLIP Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Toll-interacting protein (86-163AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TOLLIP

Target: TOLLIP (Toll Interacting Protein (TOLLIP))

Andere Bezeichnung: TOLLIP (TOLLIP Produkte)

Synonyme: IL-1RAcPIP antikoerper, 4930403G24Rik antikoerper, 4931428G15Rik antikoerper, fk22a02 antikoerper, im:7145391 antikoerper, wu:fk22a02 antikoerper, zgc:76985 antikoerper, TOLLIP antikoerper, GB17961 antikoerper, tollip antikoerper, tollip1 antikoerper, tollipa antikoerper, TOLIP antikoerper, toll interacting protein antikoerper, toll-interacting protein antikoerper, toll-interacting protein-like antikoerper, toll interacting protein L homeolog antikoerper, toll interacting protein S homeolog antikoerper, Toll-interleukine I receptor interacting protein I antikoerper, TOLLIP antikoerper, Tollip antikoerper, tollip antikoerper, LOC552034 antikoerper, LOC100169858 antikoerper, tollip.L antikoerper, tollip.S antikoerper, LOC100136122 antikoerper

Hintergrund:

Background: Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity (PubMed:11751856). Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (PubMed:25042851).

Aliases: Adapter protein antibody, FLJ33531 antibody, IL 1RAcPIP antibody, IL1RAcPIP antibody, TOLIP antibody, TOLIP_HUMAN antibody, Toll interacting protein antibody, Toll-interacting protein antibody, tollip antibody

UniProt: Q9H0E2