CD73 Antikörper (AA 27-252)

Produktnummer ABIN7596058

Der Maus Monoklonal Anti-CD73-Antikörper wurde für WB, FACS und ELISA validiert. Er ist geeignet, CD73 in Proben von Human zu detektieren.

Kurzübersicht für CD73 Antikörper (AA 27-252) (ABIN7596058)

Target: CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD73 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Klon: AT89E9

Produktdetails anti-CD73 Antikörper

Bindungsspezifität: AA 27-252

Verwendungszweck: Human 5'-Nucleotidase/CD73 antibody

Aufreinigung: protein-A affinity chromatography

Immunogen: Recombinant human 5'-Nucleotidase/CD73 (27-252aa) purified from E. coli

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Details zu CD73

Target: CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))

Andere Bezeichnung: 5'-Nucleotidase/CD73

Hintergrund: CD73 (Ecto-5-nucleotidase, 5-NT) is a membrane-bound glycoprotein that functions to hydrolyze extracellular nucleoside monophosphates into bioactive nucleoside intermediates. This enables the uptake of adenosine, inosine, and guanosine into the cell and their subsequent reconversion into ATP and GTP in the purine salvage pathway. The expression of CD73 on neuronal cells has been described during developmental processes and, on lymphocytes, CD73 serves as a maturation marker, being absent from the surface of both immature B and T cells.

NCBI Accession: NP_002517

Pathways: Synaptic Membrane, Ribonucleoside Biosynthetic Process