SUMO2/3 Antikörper (AA 1-93)
Kurzübersicht für SUMO2/3 Antikörper (AA 1-93) (ABIN7596052)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-93
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Verwendungszweck
- Human SUMO 2/3 antibody
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Immunogen
- Recombinant human SUMO2 (1-93aa) purified from E.coli
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Isotyp
- IgG2b kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing cycles
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- SUMO2/3 (Small Ubiquitin Related Modifier 2/3 (SUMO2/3))
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Andere Bezeichnung
- SUMO 2/3
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Hintergrund
- SUMO (small ubiquitin-related modifier) is the best-characterized member of a growing family ofubiquitin-related proteins. 8-11 kDa that covalently modify various intracellular proteins. It resemblesubiquitin in its structure, its ability to be ligated to other proteins. SUMO regulates cellular function of avariety of target proteins. SUMO proteins are expressed as their precursor forms. Cleavage of the residuesafter the GG region of these precursors by SUMO-specific proteases in maturation is a prerequisite forsubsequent sumoylation. Notably, SUMO2 and SUMO3 precursors have 96 % sequence identity, and recentstudies have shown protein substrates conjugated with SUMO2 or SUMO3 have similar, if not identical,biological consequences.
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NCBI Accession
- NP_008868
Target
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