EPO Antikörper (AA 28-193)

Produktnummer ABIN7596017

Dieses Anti-EPO-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von EPO in WB und ELISA. Geeignet für Human.

Kurzübersicht für EPO Antikörper (AA 28-193) (ABIN7596017)

Target: EPO (Erythropoietin (EPO))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser EPO Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: AT1C12

Produktdetails anti-EPO Antikörper

Bindungsspezifität: AA 28-193

Verwendungszweck: Human Erythropoietin/EPO antibody

Aufreinigung: protein-A affinity chromatography

Immunogen: Recombinant human Erythropoietin (28-193aa) purified from insect cell

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Details zu EPO

Target: EPO (Erythropoietin (EPO))

Andere Bezeichnung: Erythropoietin/EPO

Substanzklasse: Hormone

Hintergrund: EPO, also known as erythropoietin, is a glycoprotein hormone in the type I cytokine family and is related to thrombopoietin. Its three N-glycosylation sites, four alpha helices, and N- to C-terminal disulfide bond are conserved across species. It is primarily produced in the kidney by a population of fibroblast-like cortical interstitial cells adjacent to the proximal tubules. This protein can be found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. It also has neuroprotective activity against a variety of potential brain injuries and anti-apoptotic functions in several tissue types.

NCBI Accession: NP_000790

Pathways: JAK-STAT Signalweg, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity