Ankyrin G Antikörper

Produktnummer ABIN7595952

Der Maus Monoklonal Anti-Ankyrin G-Antikörper wurde für IHC und ICC validiert. Er ist geeignet, Ankyrin G in Proben von Human zu detektieren.

Kurzübersicht für Ankyrin G Antikörper (ABIN7595952)

Target: Ankyrin G (ANK3) (Ankyrin 3, Node of Ranvier (Ankyrin G) (ANK3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Ankyrin G Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Klon: N106-65

Produktdetails anti-Ankyrin G Antikörper

Verwendungszweck: Anti-Ankyrin-G (Staining) Antibody

Spezifität: No off-targets reported for Ankyrin-B

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale:

Description: Our Anti-Ankyrin-G (Staining) mouse monoclonal primary antibody is produced in-house from hybridoma clone N106/65. It detects human, mouse, and rat Ankyrin-G (Staining), and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Manufacturer Comment: We produce our Ankyrin-G (Staining) mouse monoclonal primary antibody from hybridoma clone N106/65. It is great in IHC, ICC and is purified by Protein A chromatography.

Aufreinigung: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.

Reinheit: > 90 % specific antibody

Immunogen: Fusion protein ~1000 amino acids of Ankyrin-G (accession number E9PE32) produced recombinantly in E. Coli

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

Dilution Range: IHC: 1:500

Dilution Range: ICC: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.74

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Haltbarkeit: 24 months

Details zu Ankyrin G

Target: Ankyrin G (ANK3) (Ankyrin 3, Node of Ranvier (Ankyrin G) (ANK3))

Andere Bezeichnung: Ankyrin-G

Hintergrund:

Synonyms: Ankyrin-3 (ANK-3) (Ankyrin-G)

Target Description: Ankyrin-G (ankyrin 3) is a member of the Ankyrin family which consists of Ankyrin R (1), Ankyrin B (2) and Ankyrin G (3) all of which are expressed in the nervous system. Ankyrins are structural proteins that aid in the attachment of integral membrane proteins with the spectrin-actin cytoskeleton, and thus targets voltage-gated sodium channels, potassium channels, cell adhesion molecules and others at the nodes of Ranvier and axonal initial segments (AIS). Variants in Ankyrin G have been linked to bipolar disorder.

Gene Name Alternatives: ANK3

Molekulargewicht: <200 kDa

Pathways: Synaptic Membrane, Maintenance of Protein Location, Skeletal Muscle Fiber Development