Ankyrin G Antikörper (AA 1690-1701)

Produktnummer ABIN462525

Produktdetails anti-Ankyrin G Antikörper

Target: Ankyrin G (ANK3) (Ankyrin 3, Node of Ranvier (Ankyrin G) (ANK3))

Bindungsspezifität: AA 1690-1701

Reaktivität: Human, Affe, Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Ankyrin G Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marke: IHC-plus™

Spezifität: Human ANK3. This antibody is expected to recognise both reported isoforms (NP_001140.2, NP_066267.2)

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Monkey, Pig (100%) Orangutan, Gibbon, Elephant, Panda, Bovine, Dog, Horse (92%) Hamster, Bat, Rabbit (83%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide C-SWQNETSSGNLE from an internal region of human ANK3 (NP_066267.2, NP_001140.2). Percent identity by BLAST analysis: Human, Gorilla, Monkey, Pig (100%), Orangutan, Gibbon, Elephant, Panda, Bovine, Dog, Horse (92%), Hamster, Bat, Rabbit (83%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (3.75 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 3.75 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu Ankyrin G

Target: Ankyrin G (ANK3) (Ankyrin 3, Node of Ranvier (Ankyrin G) (ANK3))

Andere Bezeichnung: ANK3 / ANKYRIN-G (ANK3 Produkte)

Synonyme: ANK3 antikoerper, ankyrin-G antikoerper, 2900054D09Rik antikoerper, AI314020 antikoerper, Ank-3 antikoerper, AnkG antikoerper, Ankyrin-3 antikoerper, Ankyrin-G antikoerper, ANKYRIN-G antikoerper, ankyrin 3 antikoerper, ankyrin 3, node of Ranvier (ankyrin G) antikoerper, ankyrin 3, epithelial antikoerper, ANK3 antikoerper, legA6 antikoerper, PB000272.02.0 antikoerper, PY00018 antikoerper, ank3 antikoerper, Ank3 antikoerper

Hintergrund: Name/Gene ID: ANK3

Synonyms: ANK3, ANKYRIN-G, ANK-3, Ankyrin G119, Ankyrin-3

Gen-ID: 288

NCBI Accession: NP_066267, NP_001140

UniProt: Q12955

Pathways: Synaptic Membrane, Maintenance of Protein Location, Skeletal Muscle Fiber Development