CADM1 Antikörper (AA 257-388) (FL550)

Produktnummer ABIN7595572

Dieses Anti-CADM1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CADM1 in ICC. Geeignet für Maus.

Kurzübersicht für CADM1 Antikörper (AA 257-388) (FL550) (ABIN7595572)

Target: CADM1 (Cell Adhesion Molecule 1 (CADM1))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CADM1 Antikörper ist konjugiert mit FL550

Applikation: Immunocytochemistry (ICC)

Klon: L45-30

Produktdetails anti-CADM1 Antikörper (FL550)

Bindungsspezifität: AA 257-388

Verwendungszweck: Anti-SynCAM1 Antibody FL550 Conjugate

Spezifität: No cross-reactivity with SynCAM2 or SynCAM3

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale:

Description: Our Anti-SynCAM1 mouse monoclonal primary antibody is produced in-house from hybridoma clone L45/30. It detects human, mouse, and rat SynCAM1, and is purified by Protein A chromatography. It is great for use in ICC.

Manufacturer Comment: We produce our SynCAM1 mouse monoclonal primary antibody from hybridoma clone L45/30. It is great in ICC and is purified by Protein A chromatography.

Aufreinigung: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Reinheit: > 90 % specific antibody

Immunogen: Fusion protein amino acids 257-388 of mouse SynCAM1 (accession number Q8R5M8), recognizes 1.4b isoform only (epitope narrowed to GLTQLPNSAEELDSEDLS) produced recombinantly in E. Coli

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Haltbarkeit: 12 months

Details zu CADM1

Target: CADM1 (Cell Adhesion Molecule 1 (CADM1))

Andere Bezeichnung: SynCAM1

Hintergrund:

Synonyms: Cell adhesion molecule 1 (Immunoglobulin superfamily member 4) (IgSF4) (Nectin-like protein 2) (NECL-2) (Spermatogenic immunoglobulin superfamily) (SgIgSF) (Synaptic cell adhesion molecule) (SynCAM) (Tumor suppressor in lung cancer 1) (TSLC-1)

Target Description: SynCAM1 cell adhesion molecule, Immunoglobulin superfamily member 4 (IgSF4), or Nectin-like protein 2 (NECL-2) is encoded by the gene CADM1 and is a member of the Immunoglobulin-like Cell Adhesion Molecules family. SynCam1 is a cell adhesion molecule involved in many cell processes including the mediation of cell-cell adhesion and assembly, neuronal migration axon growth and differentiation. SynCAM1 is expressed in many tissue types including, brain, lung, kidney, heart, spleen and liver. Diseases associated with this gene include Retroperitoneal Fibrosis and Neuromyelitis Optica Spectrum Disorder.

Gene Name Alternatives: Cadm1 Igsf4 Necl2 Ra175 Syncam SynCam1 Tslc1

Molekulargewicht: 50 kDa

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Activated T Cell Proliferation