DNMT3L Antikörper (AA 1-387) (FL550)

Produktnummer ABIN7595543

Dieses Maus Monoklonal-Antikörper erkennt spezifisch DNMT3L in ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für DNMT3L Antikörper (AA 1-387) (FL550) (ABIN7595543)

Target: DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DNMT3L Antikörper ist konjugiert mit FL550

Applikation: Immunocytochemistry (ICC)

Klon: N117-9

Produktdetails anti-DNMT3L Antikörper (FL550)

Bindungsspezifität: AA 1-387

Verwendungszweck: Anti-DNMT3L Antibody FL550 Conjugate

Spezifität: No off-targets reported for DNMT3A or DNMT3B

Kreuzreaktivität: Human

Produktmerkmale:

Description: Our Anti-DNMT3L mouse monoclonal primary antibody is produced in-house from hybridoma clone N117/9. It detects human DNMT3L, and is purified by Protein A chromatography. It is great for use in ICC.

Manufacturer Comment: We produce our DNMT3L mouse monoclonal primary antibody from hybridoma clone N117/9. It is great in ICC and is purified by Protein A chromatography.

Aufreinigung: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Reinheit: > 90 % specific antibody

Immunogen: Fusion protein amino acids 1-387 (full-length) of human DNMT3L (accession number BAA95556) produced recombinantly in E. Coli

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Haltbarkeit: 12 months

Details zu DNMT3L

Target: DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))

Andere Bezeichnung: DNMT3L

Hintergrund:

Synonyms: DNA (cytosine-5)-methyltransferase 3-like

Target Description: DNA (cytosine-5)-methyltransferase 3-like or DNMT3L is encoded by the gene DNMT3L. DNMT3l is a nuclear, catalytically inactive, regulatory factor of DNA methyltransferases. DNMT3L mediates transcriptional repression through interaction with histone deacetylase 1. It is thought to be required for the establishment of maternal genomic imprints. DNMT3L is expressed in several tissues including testis, ovary, and thymus. Diseases associated with DNMT3L include Testicular Spermatocytic Seminoma and Immunodeficiency-Centromeric Instability-Facial Anomalies Syndrome.

Gene Name Alternatives: DNMT3L

Molekulargewicht: 45 kDa