Beclin 1 Antikörper

Produktnummer ABIN7595319

Der Huhn Polyklonal Anti-Beclin 1-Antikörper wurde für WB und IHC validiert. Er ist geeignet, Beclin 1 in Proben von Maus zu detektieren.

Kurzübersicht für Beclin 1 Antikörper (ABIN7595319)

Target: Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

Reaktivität: Maus

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser Beclin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Beclin 1 Antikörper

Verwendungszweck: Chicken antibody to Beclin-1

Spezifität: Specific for Beclin-1.

Kreuzreaktivität: Human, Marmoset, Maus, Ratte

Kreuzreaktivität (Details): Other species not yet tested.

Aufreinigung: Purified IgY

Immunogen: Truncated recombinant mouse Beclin-1 conjugated to blue carrier protein has been used as the antigen. The antigen shares 99% identity with human and rat sequences.

Isotyp: IgY

Anwendungsinformationen

Applikationshinweise: IHC WB. Use at a dilution of 1 : 1000. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term.

Haltbarkeit: 12 months

Details zu Beclin 1

Target: Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

Andere Bezeichnung: Beclin-1

Hintergrund: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation metamorphosis non-apoptotic cell death and aging. Reduced levels of autophagy have been described in some malignant tumors and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. It may play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus. May play a role in autophagy. SUBCELLULAR LOCATION: Cytoplasm. Golgi apparatus membrane, Peripheral membrane protein. Note: Expressed in dendrites and cell bodies of cerebellar Purkinje cells TISSUE SPECIFICITY: Ubiquitous

Pathways: Autophagie