OLIG2 Antikörper

Produktnummer ABIN7595310

Der Meerschweinchen Polyklonal Anti-OLIG2-Antikörper wurde für WB, IHC und FACS validiert. Er ist geeignet, OLIG2 in Proben von Maus zu detektieren.

Kurzübersicht für OLIG2 Antikörper (ABIN7595310)

Target: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Reaktivität: Maus

Wirt: Meerschweinchen

Klonalität: Polyklonal

Konjugat: Dieser OLIG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktdetails anti-OLIG2 Antikörper

Verwendungszweck: Guinea pig antibody to Olig2

Spezifität: Specific for Olig2.

Kreuzreaktivität: Maus, Ratte

Kreuzreaktivität (Details): Other species not yet tested.

Aufreinigung: Whole serum

Immunogen: A synthetic peptide from mouse Olig2 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.

Anwendungsinformationen

Applikationshinweise: IHC WB Flow Cyt. A dilution of 1 : 500 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Haltbarkeit: 12 months

Details zu OLIG2

Target: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Andere Bezeichnung: Olig2

Hintergrund: Function: Required for oligodendrocyte and motor neuron specification in the spinal cord as well as for the development of somatic motor neurons in the hindbrain. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development. Subcellular location: Nucleus. Cytoplasm Tissue specificity: Expressed in the brain in oligodendrocytes. Strongly expressed in oligodendrogliomas while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable. Involvement in disease: A chromosomal aberration involving OLIG2 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(14,21)(q11.2,q22) with TCRA.