SSTR2 Antikörper (Extracellular) (FITC)

Produktnummer ABIN7582079

Der Kaninchen Polyklonal Anti-SSTR2-Antikörper wurde für FACS und LCI validiert. Er ist geeignet, SSTR2 in Proben von Ratte zu detektieren.

Kurzübersicht für SSTR2 Antikörper (Extracellular) (FITC) (ABIN7582079)

Target: SSTR2 (Somatostatin Receptor 2 (SSTR2))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SSTR2 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS), Live Cell Imaging (LCI)

Produktdetails anti-SSTR2 Antikörper (FITC)

Bindungsspezifität: AA 30-43, Extracellular

Verwendungszweck: A Rabbit polyclonal antibody to Somatostatin Receptor Type 2 (extracellular) conjugated to fluorescein isothiocyanate (FITC) fluorophore.

Sequenz: (C)GSNQTEPYYD MTSN

Spezifität: Extracellular, N-terminus

Homologie: Mouse - identical, human- 12,14 amino acid residues identical

Produktmerkmale: Anti-Somatostatin Receptor Type 2 (extracellular) Antibody (ABIN7043765, ABIN7045268 and ABIN7045269) is a highly specific antibody directed against an extracellular epitope of the rat protein. The antibody can be used in western blot, immunohistochemistry and immunocytochemistry applications. It has been designed to recognize SSTR2 from mouse, human and rat samples. Anti-Somatostatin Receptor Type 2 (extracellular)-FITC Antibody (ABIN7043765, ABIN7045268 and ABIN7045269-F) is directly conjugated to fluorescein isothiocyanate (FITC). This labeled antibody can be used in immunofluorescent applications such as direct flow cytometry and live cell imaging.

Aufreinigung: Affinity purified on immobilized antigen.

Immunogen: (C)GSNQTEPYYDMTSN, corresponding to amino acid residues 30-43 of rat SSTR2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Antigen preadsorption control: 1 μg peptide per 1 μg antibody

Kommentare:

Negative Control: (ABIN7582044)

Blocking Peptide: (ABIN7237239)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 50 μL double distilled water (DDW).

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Details zu SSTR2

Target: SSTR2 (Somatostatin Receptor 2 (SSTR2))

Andere Bezeichnung: SSTR2

Hintergrund: SSTR2, SS2R, Smstr2, SRIF1A,Somatostatin is a small cyclic peptide that is widely expressed throughout the central nervous system and peripheral tissues.1 In peripheral tissues, somatostatin exerts inhibitory effects on secretion processes, whereas in the brain, it acts as a neurotransmitter in both a stimulatory and an inhibitory manner.1,2Somatostatin mediates its action via six high affinity G-protein coupled receptors (SSTR1, SSTR2a, SSTR2b, SSTR3, SSTR4, and SSTR5), which are encoded by five genes.1,2 Expression of the different receptors is developmentally regulated in a time- and tissue-specific manner.2Somatostatin receptors have been found on a variety of neuroendocrine tumors, such as paragangliomas, carcinoids, and breast tumors.3 Synthetic peptide derivatives of somatostatin have been successfully used in the treatment of neuroendocrine malignancies and in vivo imaging of tumors that are positive for somatostatin receptors.4In general, SSTR2 is the most common SSTR subtype found in human tumors, followed by SSTR1, with SSTR3 and SSTR4 being less common.

Gen-ID: 54305

UniProt: P30680